Preparation and characterization of as-extruded Mg–Sn alloys for orthopedic applications

Zhao, Chaoyong; Pan, Fusheng; Zhao, Shuang; Pan, Hucheng; Song, Kai; Tang, Aitao

doi:10.1016/j.matdes.2014.12.041

Cited by 98 publications

(37 citation statements)

References 33 publications

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“…Research toward the development of lightweight magnesium alloys for various structural applications in transportation vehicles is driven by more strict demand for energy saving and limited CO 2 emission [1][2][3][4][5][6][7]. Enhancing mechanical properties of the Mg alloys is an essential requirement for their commercial applications [8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Enhancing mechanical properties of Mg–Sn alloys by combining addition of Ca and Zn

et al. 2015

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Section: Introductionmentioning

confidence: 99%

Enhancing mechanical properties of Mg–Sn alloys by combining addition of Ca and Zn

et al. 2015

Self Cite

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“…With 14 of 31 significant regression analyses, the relation between controlled mechanical integrity and degradation (MR 1) and the composition (EC A) verifies and reflects the current research focus on the composition to improve and control the corrosion process. Various biocompatible and nontoxic magnesium‐based alloys have already been investigated, such as: Mg–Ca (Li et al, ; Seong & Kim, ; Zeng et al, ), Mg–Zn (Zhang et al, ), Mg‐Zr (Li et al, ), Mg–Sr (Bornapour, Celikin, & Pekguleryuz, ; Gu et al, ; Zhao, Pan, & Pan, ), Mg–Si (Gil‐Santos, Marco, Moelans, Hort, & Van der Biest, ), Mg–Sn (Zhao et al, ), Mg–Ge (Bian et al, ), Mg–REE (Hort et al, ), Mg–Zn–Ca (Cipriano et al, ; Fazel Anvari‐Yazdi et al, ) and Mg–Si–Ca–Zn (Zhao et al, ). The results of the regression analysis also confirmed the interrelation between the control of degradation (MR 1) and the structure (EC C).…”

Section: Discussionmentioning

confidence: 99%

Development of magnesium implants by application of conjoint‐based quality function deployment

Siefen

Höck

2019

J Biomedical Materials Res

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Biodegradable magnesium‐based implants are the subject of a great deal of research for different orthopedic and vascular applications. The targeted design and properties depend on the specific medical function and location in the body. Development of the biomaterial requires a comprehensive understanding of the biological interaction between the implant and the host tissue, as well as of the behavior in the physiological environment in vivo. Research into and the development of innovative magnesium implants entails interdisciplinary research efforts and communication between materials science, bioscience, and medical experts. The present study provides a transparent planning and communication tool for market‐oriented implant development processes. The objective was to identify medical needs at an early stage of the development process and to quantify the importance of the engineering characteristics of different research fields that cater to specific implant requirements. The method is demonstrated by the performance of a survey‐based conjoint analysis, which was integrated into a quality function deployment approach. Twenty‐seven medical professionals and 29 biomaterial scientists assessed the importance of identified medical requirements, whereby the control of mechanical integrity and degradation along with nontoxicity and nonimmunogenicity showed the highest number of preferences. The evaluation of implant options by 31 experts indicated that the engineering characteristic with the highest importance was the condition and sterilization of the surface. These values can be used to set priorities in strategic decisions. Research trials can be aligned to medical preferences, ensuring high product quality and an effective development process. This is the first paper to report on the application of conjoint‐based quality function deployment in biomaterial research.

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“…Alloys such as Mg-1-wt.%-Sn and Mg-3-wt.%-Sn alloys were suitable for use as biodegradable orthopedic implants. (10) Additionally, many researchers have studied the mechanical properties and biocorrosion characteristics of the Mg-Sn alloys. Cheng et al investigated the mechanical properties of the extruded Mg-Sn alloys with 6-10 wt.% Sn and found that the tensile and compressive strengths increased with the Sn content while the yield asymmetry was the opposite.…”

Section: Introductionmentioning

confidence: 99%

Microstructure and Wear Property of As-cast Mg-2wt.%-Sn Alloys after Different Heat Treatment Processes

Chen

Wang

Chao

et al. 2019

Sensors and Materials

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The developments of biodegradable materials for orthopaedic implants has been progressing rapidly for decades. Biodegradable implants can eliminate the need for a second surgery and avoid the possible risks of retained metallic implants, such as corrosion or strength weakening. Magnesium (Mg) alloy is one of the potential materials for biodegradable implants because of its good biocompatibility and biodegradability. In this study, the microstructures and mechanical properties, especially the wear behavior and friction characteristics of Mg-Sn alloys, were investigated. Mg-Sn alloys fabricated by the ingot casting method were applied to different heat treatments, and then subjected to the pin-on-disc wear test. Experimental results showed that the Mg-Sn alloy processed by solution heat treatment (SHT) at 520 ℃ and quenching had the best wear resistance and lowest coefficient of friction (COF). The decrease in the amount of hard precipitate Mg 2 Sn and the solid-solution strengthening induced by the excess Sn atoms in the Mg matrix were the main causes of the enhancement of the wear properties of the Mg-Sn alloy upon SHT, compared with as-cast Mg-Sn alloy and the Mg-Sn alloys made by other heat treatments.

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Preparation and characterization of as-extruded Mg–Sn alloys for orthopedic applications

Cited by 98 publications

References 33 publications

Enhancing mechanical properties of Mg–Sn alloys by combining addition of Ca and Zn

Enhancing mechanical properties of Mg–Sn alloys by combining addition of Ca and Zn

Development of magnesium implants by application of conjoint‐based quality function deployment

Microstructure and Wear Property of As-cast Mg-2wt.%-Sn Alloys after Different Heat Treatment Processes

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