Preparation and characterization of chitosan/graphene oxide nanocomposite coatings on Mg–2 wt% Zn scaffold by pulse electrodeposition process

Abstract

Mg and its alloys are biodegradable and mechanically strong materials, which can be used for an orthopedic implant and device applications, but corrosion rate of these alloys is high. In this research, the nanocomposite coatings of chitosan (CS)/graphene oxide (GO) were fabricated to improve the corrosion resistance of the Mg–2 wt% Zn scaffold. The contents of the GO nanosheets and the pulse electrodeposition process parameters, including peak current density (CD) and duty cycle (DC), will also be investigated. The Mg–2 wt% Zn as a substrate of the scaffold was prepared using a powder metallurgy process. The influence of the porosity was studied on the microstructure fabricated scaffolds. The coating microstructures and morphologies were investigated by Raman spectroscopy, x-ray diffraction, thermogravimetric analysis, and SEM. The atomic force microscopy was performed to study the thickness of the nanocomposite coatings. The zeta potential measurement was conducted for the dispersion of the GO nanosheets in the CS matrix. The obtained results showed that the optimum conditions to fabricate a uniform CS/GO coating on the scaffolds were 2 wt% GO, CD = 20 mA cm−2, and DC = 0.5. The pH, time and temperature for the fabrication of the coatings were conducted at 5, 20 min, and 37 °C, respectively. Additionally, the potentiodynamic polarization measurement in simulated body fluid indicated that the CS/GO coatings could provide effective protection of the scaffolds against corrosion. Additionally, the optimum sample obtained from the aspect of the corrosion behavior demonstrated adequate biocompatibility with proper adhesion of mouse fibroblast cells (L929) on the CS–2 wt% GO coating.

Advancements in Fabrication and Application of Chitosan Composites in Implants and Dentistry: A Review

“…Different techniques are applied to the development of three-dimensional composite scaffolds of chitosan-CNM like freeze-drying and thermally induced phase separation (TIPS) for biomedical implant applications. Some of these synthesis techniques have been used for these mentioned compositions by a number of a researcher like electrodeposition for biomedical implant applications, 3D printing for biomedical application and production possibility of the antimicrobial filaments, freeze-drying for antimicrobial activity, and covalent crosslinking for bone tissue engineering [ 103 , 104 , 105 , 106 , 107 ].…”

Recent Progress in Surface Modification of Mg Alloys for Biodegradable Orthopedic Applications

“…The porous nanostructure significantly affected the wettability to obtain a superhydrophobic surface with a higher contact angle. Hamghavandi et al (2021) studied the effect of PED process parameters and the composition of nanocomposite coating with chitosan and graphene oxide on the Mg-Zn scaffold with a porosity closer to that of bone. The best performance was obtained for a composition of chitosan with 2 wt.% GO when coated using a current density of 20 mA/cm 2 and a duty cycle of 0.5.…”

Nanoscale hydroxyapatite/chitosan polymer coatings: Synthesis and characterization

“…The study conducted by Seyedraoufi et al aimed to examine the PED method on the characteristics of nHA covering on the with a 2% weight of Zn and scaffold, with the ultimate goal of evaluating its suitability for use in the bone tissues 33 . The experimental findings by Hamghavandi et al 34 indicated that the optimal factors to synthesize a CS/GO coating on the Mg scaffolds were 2% weight GO, j = 20 mA/cm 2 , and a duty cycle of 0.5. Notably, limited research has been carried out regarding enhancing the resistance to corrosion and biological compatibility of nHA/CS coating on the Mg‐2Zn scaffold by employing the PED technique.…”