Preparation and characterization of crosslinked starch microspheres using a two-stage water-in-water emulsion method

Water-in-Water Emulsion as a New Approach to Produce Mesalamine-Loaded Xylan-Based Microparticles

“…The ATR-IR results also revealed that the bond P=O formed during the crosslinking process between the STMP and the polysaccharides was not observed. This phenomenon was equally observed for the empty and loaded XBM-Ca-F9 and might reveal a low degree of crosslinking, which was suggested by Li and co-workers (2012) [15]. The presence of a sharp peak at the 848 cm −1 region was observed for the XBM-Ca-F9 loaded with 5-ASA ( Figure 6B (II)), while it was not seen on the empty XBM-Ca-F9 ( Figure 6B (I)).…”

“…The reports about microparticles prepared by the water-in-water emulsion technique hardly ever describe the encapsulation of active molecules [14][15][16]. Nonetheless, when tried, the encapsulated molecules are mostly biomolecules, such as proteins and peptides [17].…”

Designing polymeric microparticles for biomedical and industrial applications

“…Generally, the methods used to prepare starch microparticles include a cross-linking step, during or after particle formation [60,61,63]. Since starch is a hydrophilic polymer, the crosslinking of the polyssacharide chains is required to obtain microparticles that are resistant to dissolution in the physiological environment.…”

Aqueous Two-Phase Systems for Microencapsulation in Food Applications

“…A very similar methodology was used by Li et al (2012), when their technique to prepare starch microspheres crosslinked using TSTP in a W/O system (Li et al, 2009) was converted to a W/W system where starch and PEG are the phase-forming polymers (Li et al, 2012). Particles produced in the two systems were compared and found to be similar, albeit with some differences in yield and crosslinking degree.…”