Preparation and characterization of hybrid chitosan-silver nanoparticles (Chi-Ag NPs); A potential antibacterial agent

Senthilkumar, P.; Yaswant, Govindaraj; Kavitha, S.; Chandramohan, E.; Kowsalya, G.; Vijay, R.; Sudhagar, B.; Kumar, Dileep

doi:10.1016/j.ijbiomac.2019.08.234

Cited by 76 publications

(33 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, electrostatic deposition could be applied for the formation of CCNs either in already formed negatively charged nanoparticles or during the formation of the nanoparticles ( Figure 7 ). Both approaches have been used to prepare coated polymeric nanoparticles, lipid nanoparticles and metal-based nanoparticles as well [ 183 , 186 , 188 , 189 , 206 , 207 , 208 ]. Especially, natural products such as curcumin [ 209 ] and resveratrol [ 192 ] were successfully encapsulated in chitosan-coated nanoformulations where the coating process was accomplished using pre-formed nanoemulsions and lipid microparticles, respectively.…”

Section: Chitosan-coated and Modified Chitosan Nanosystems Encapsumentioning

confidence: 99%

“…Chitosan-coated silver nanoparticles (AgNPs) are an exceptional example of hybrid nanosystem developed for the enhancement of the antibacterial activity against pathogenic Gram-negative (e.g., E. coli ) or Gram-positive bacteria such as Staphylococcus aureus [ 226 ]. In particular, Senthilkumar et al in 2019 presented the green synthesis of silver nanoparticles coated with chitosan using leaf extract of T. portulacifolium as reducing agent [ 208 ]. The obtained spherical shaped nanoparticles have cubic fluorite structure presenting average particles size ranging from 3.2 nm to 44.8 nm as it was indicated by TEM analysis.…”

Section: Chitosan-coated and Modified Chitosan Nanosystems Encapsumentioning

confidence: 99%

See 1 more Smart Citation

Nanosystems for the Encapsulation of Natural Products: The Case of Chitosan Biopolymer as a Matrix

et al. 2020

View full text Add to dashboard Cite

Chitosan is a cationic natural polysaccharide, which has emerged as an increasingly interesting biomaterialover the past few years. It constitutes a novel perspective in drug delivery systems and nanocarriers’ formulations due to its beneficial properties, including biocompatibility, biodegradability and low toxicity. The potentiality of chemical or enzymatic modifications of the biopolymer, as well as its complementary use with other polymers, further attract the scientific community, offering improved and combined properties in the final materials. As a result, chitosan has been extensively used as a matrix for the encapsulation of several valuable compounds. In this review article, the advantageous character of chitosan as a matrix for nanosystemsis presented, focusing on the encapsulation of natural products. A five-year literature review is attempted covering the use of chitosan and modified chitosan as matrices and coatings for the encapsulation of natural extracts, essential oils or pure naturally occurring bioactive compounds are discussed.

show abstract

Section: Chitosan-coated and Modified Chitosan Nanosystems Encapsumentioning

confidence: 99%

Section: Chitosan-coated and Modified Chitosan Nanosystems Encapsumentioning

confidence: 99%

Nanosystems for the Encapsulation of Natural Products: The Case of Chitosan Biopolymer as a Matrix

et al. 2020

View full text Add to dashboard Cite

show abstract

“…AgNPs are used as deodorizers and disinfectants [ 9 , 10 ] by incorporating them into garments, bandages, coatings and food containers; in addition, they are used to purify drinking water, and recently, as an insecticide to control the attack of pests on various crops [ 11 ]. Most of these applications of AgNPs are attributed to their size- and shape-dependent unique chemical and physical characteristics [ 12 , 13 , 14 ]. Nanoparticles are usually synthesized by chemical or biological methods [ 15 , 16 , 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Eco Friendly Approach for Synthesis, Characterization and Biological Activities of Milk Protein Stabilized Silver Nanoparticles

et al. 2020

View full text Add to dashboard Cite

Today, the overall occurrence of re-emerging and rising illnesses has been a serious load on economies as well as public health. Here, we describe a simple, nontoxic and eco-friendly method for the synthesis of milk protein (MP)-stabilized silver nanoparticles (MP-s-AgNPs) using ultrahigh-temperature full cream milk. Highly stable AgNPs were prepared with a fair control over their size, without using any reducing or stabilizing agent, and their formation was attributed to the presence of the MP casein. Ag+ ion reduction was possibly caused by the MPs. The synthesized MP-s-AgNPs were characterized in detail by ultraviolet-visible spectroscopy, Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, transmission electron microscopy and dynamic light scattering. MP-s-AgNPs showed inhibitory activity against both Gram-positive (Bacillus subtilis and Staphylococcus aureus) and Gram-negative microorganisms (Salmonella typhi and Escherichia coli). Moreover, MP-s-AgNPs were found to be more toxic to bacteria than to fungi (Aspergillus fumigatus, Aspergillus ochraceus and Penicillium chrysogenum).

show abstract

“…Accordingly, the “green” chemistry implies the design, development, and application of chemical products and process to reduce or eliminate the use or generation of hazardous substances to human health and the environment [ 10 ]. As has been reported in literature, the green chemistry routes for synthesis of AgNPs consider biopolymers such as chitosan, poly(lactic acid), sodium alginate, cellulose, and carboxymethyl-cellulose as both reducing and capping agents [ 11 , 12 , 13 , 14 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Influence of Polysaccharides’ Molecular Structure on the Antibacterial Activity and Cytotoxicity of Green Synthesized Composites Based on Silver Nanoparticles and Carboxymethyl-Cellulose

et al. 2020

View full text Add to dashboard Cite

In this paper we report on the influence of polysaccharides’ molecular structure on the antibacterial activity and cytotoxicity of composites based on silver nanoparticles (AgNPs) immobilized into carboxymethyl-cellulose (CMC). These composites were green synthesized from the reduction of silver ions into aqueous solutions of the polysaccharide, using CMC with different degree of substitution (DS) and molecular weight (Mw). The composites were characterized by transmission electron microscopy (TEM), as well as infrared (ATR-FTIR), ultraviolet (UV-Vis), Raman, and X-ray photo-electron (XPS) spectroscopic techniques. The antibacterial activity was evaluated with minimum inhibitory concentration against Enterococcus faecalis. The cytotoxicity of composites was assessed against human gingival fibroblast. Experimental evidence suggests that particle size distribution and morphology of AgNPs change according to the quantity of silver precursor added to the reaction, as well as the DS and Mw of CMC used for composites preparation. This is related to the dispersion of silver precursor into aqueous solutions of the polysaccharide and the formation of Ag-O coordination bonds among AgNPs and COO− moieties of CMC. Moreover, these coordination bonds modify the ability of nanoparticles to produce and release Ag+ into aqueous dispersion, adjusting their antibacterial activity and the induction of cytotoxicity into the tested biological environments.

show abstract

Preparation and characterization of hybrid chitosan-silver nanoparticles (Chi-Ag NPs); A potential antibacterial agent

Cited by 76 publications

References 38 publications

Nanosystems for the Encapsulation of Natural Products: The Case of Chitosan Biopolymer as a Matrix

Nanosystems for the Encapsulation of Natural Products: The Case of Chitosan Biopolymer as a Matrix

Eco Friendly Approach for Synthesis, Characterization and Biological Activities of Milk Protein Stabilized Silver Nanoparticles

Influence of Polysaccharides’ Molecular Structure on the Antibacterial Activity and Cytotoxicity of Green Synthesized Composites Based on Silver Nanoparticles and Carboxymethyl-Cellulose

Contact Info

Product

Resources

About