2019
DOI: 10.1093/rb/rbz050
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Preparation and characterization of methacrylated gelatin/bacterial cellulose composite hydrogels for cartilage tissue engineering

Abstract: Methacrylated gelatin (GelMA)/bacterial cellulose (BC) composite hydrogels have been successfully prepared by immersing BC particles in GelMA solution followed by photo-crosslinking. The morphology of GelMA/BC hydrogel was examined by scanning electron microscopy and compared with pure GelMA. The hydrogels had very well interconnected porous network structure, and the pore size decreased from 200 to 10 µm with the increase of BC content. The composite hydrogels were also characterized by swelling experiment, X… Show more

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Cited by 77 publications
(45 citation statements)
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“…Nadezhda et al also considered that the swelling capacity of the microspheres prepared by alginate and GA was mainly regulated by the content of GA (Lewandowska-Łańcucka et al 2017). The higher swelling capacity of the hydrogels enhances cell proliferation and cell viability by facilitating transport of nutrients into the hydrogels (Annabi et al 2011;Gu et al 2020). That corresponds well with our findings.…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…Nadezhda et al also considered that the swelling capacity of the microspheres prepared by alginate and GA was mainly regulated by the content of GA (Lewandowska-Łańcucka et al 2017). The higher swelling capacity of the hydrogels enhances cell proliferation and cell viability by facilitating transport of nutrients into the hydrogels (Annabi et al 2011;Gu et al 2020). That corresponds well with our findings.…”
Section: Discussionsupporting
confidence: 92%
“…1C-G). Swelling capacity reflects the hydrophilic character and water retention capacity of hydrogels, and is also an important factor for predicting nutrient transfer within hydrogels (Gu et al 2020). After being immersed in PBS for 24 h, mTG/GA, C-mTG/GA, and A-mTG/GA hydrogels were slightly expanded, whereas the volumes of chitosan and alginates hydrogels almost remained unchanged.…”
Section: Characterization Of Hydrogels Gelation Time and Appearance Omentioning
confidence: 99%
“…Swelling capacity reflects the hydrophilic character and water retention capacity of hydrogels, and is also an important factor for predicting nutrient transfer within hydrogels ( Gu et al, 2020 ). After being immersed in PBS for 24 h, mTG/GA, C-mTG/GA, and A-mTG/GA hydrogels were slightly expanded, whereas the volumes of chitosan and alginates hydrogels almost remained unchanged.…”
Section: Resultsmentioning
confidence: 99%
“…Nadezhda et al also considered that the swelling capacity of the microspheres prepared by alginate and GA was mainly regulated by the content of GA ( Lewandowska-Łańcucka et al, 2017 ). The higher swelling capacity of the hydrogels enhances cell proliferation and cell viability by facilitating transport of nutrients into the hydrogels ( Annabi et al, 2011 ; Gu et al, 2020 ). That corresponds well with our findings.…”
Section: Discussionmentioning
confidence: 99%
“…There were 16 literatures that explicitly refer to the light intensity of the experiment, among which units in Bektas, 46 Ratheesh, 48 and Gu 54 cannot be unified with others. So these three articles were excluded, and the remaining 13 articles were divided into two groups according to the light intensity: I ≤ 10 mW/cm 2 and I > 10 mW/cm 2 ( I is the light intensity).…”
Section: Results and Discussionmentioning
confidence: 99%