Preparation and Characterization of Montmorillonnite/Tamarind Gum/ Sodium Alginate Composite Gel Beads

Abstract

Composite gel beads of tamarind gum and sodium alginate were prepared in a well-shaped spherical form with a size range of 23 mm by adding montmorillonite (MMT 0.5 wt%). The properties of the composite beads, such as morphological, thermal stability, and functional groups of the beads, were characterized by different techniques (i.e., SEM, DSC, and FT-IR). The X-ray diffraction and the swelling behavior responding to pH of the composite beads were also studied. The MMT made the beads formed beautiful 3D reticulation and added the beads' stability. The prepared composite gel beads have potential industrial applications such as polymeric carrier and support in biotechnology and biochemistry field.

Formulation and <i>in vitro</i> evaluation of natural gum-based microbeads for delivery of Ibuprofen

“…In spite of the extensive use of synthetic polymers in the formulation of microbeads, the development of natural biodegradable polymer-based systems for controlled drug delivery continues to be of interest [3]. Biodegradable polymers including natural gums and starches have been utilized as carriers because of their relative availability, capability for multiple chemical modifications and compatibility [3][4][5].…”

Novel interpenetrated polymer network microbeads of natural polysaccharides for modified release of water soluble drug: in-vitro and in-vivo evaluation

“…It is used as a stabilizer, thickener, gelling agent and binder in the food and pharmaceutical industry [12] . Recently, TSP has been used as a carrier for drug delivery applications [13,14] . Sodium alginate, a natural polysaccharide, is composed of 1,4‐linked‐ β ‐ d ‐mannuronic acid and α ‐ l ‐guluronic acid residues, and used as a gelling agent in the food industry.…”

A review study on chemical composition and molecular structure of newly plant gum exudates and seed gums

“…It is rich in a high molecular weight polysaccharide (~65-72%) with the molecular weight of 720-880 kDa (Freitas et al, 2005;Kumar & Bhattacharya, 2008). However, different molecular weight ranging from 2.5 × 10 5 to 6.5 × 10 5 Da was reported in the previous study (Zhang, Xu, Zhang, & Du, 2008).…”

“…An approximately 80% of glucose remains are replaced by xylose residues (1-6 linked), which themselves replaced in part by p-1-2 galactose residues ( Fig. 6) (Goyal, Kumar, & Sharma, 2007;Zhang et al, 2008). TSP is a promising polymer mainly used as stabilizer, thickener, gelling agent, and binder in food and pharmaceutical industries.…”

“…TSP solution has the proper resistance against acid and thermal process. It can form a gel which is mainly used as a thickening and stabilizing agent in the food industry (Zhang et al, 2008). TSP is also known as a novel drug delivery system and bioadhesive agent in pharmaceutical products with non-carcinogenicity, Table 8 Chemical composition of Iranian and Indian basil seeds, crude and pure BSG a (%).…”