Preparation and Characterization of Nano-Selenium Decorated by Chondroitin Sulfate Derived from Shark Cartilage and Investigation on Its Antioxidant Activity

Chen, Jianping; Chen, Xuehua; Li, Jiarui; Luo, Baozhen; Fan, Tugui; Li, Rui; Liu, Xiaofei; Song, Bingbing; Jia, Xuejing; Zhong, Saiyi

doi:10.3390/md20030172

Cited by 13 publications

(13 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results were in agreement with the JCPDS card. The results agreed with what was stated by [10] and [18].…”

Section: X-ray Diffraction Of Se-npssupporting

confidence: 93%

Determining the Efficacy of Selenium Nanoparticles (Se-NPs) Conjugated with Zinc and Synthesized Using Aspergillus niger on some Immunological Parameters of Induced Immunosuppressed Rats

Abd Al-Aziz,

Thalij,

Zakaria

2023

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

This research was aimed to isolation and identification of Aspergillus niger from different location of garden in Tikrit university, to used in Se-NPs synthesis alone and conjugated with Zn, then its characterizes by detected the spectroscopy, shape and size of the nanoparticles, also determine the efficacy each of Se-NPs or Zn alone or after conjugated when orally dosage to laboratory rats that’s induced immunosuppressed by sandimmune on IgA, IgG and IL-6. The results were found that ability to isolated and identified the Aspergillus niger from different sites in the gardens of the Tikrit University. The synthesis of Se-NPs were obtained by converting sodium selenite (Na2SeO4) used the Aspergillus niger extract, also they obtained the Se-NPs conjugated with Zn. The confirm of synthesis were inferred through the color was changed to oranges. The value of these particles alone or their genera appeared at a wavelength of 262 and 269 nm, respectively. The scanning electron microscope (SEM) showed spherical particle shapes and sizes at 52.90 nm which were confirmed by X-ray diffraction. The orally dosage of Se-NPs for male laboratory rats alone or in combination induced immunusupressed affected the renormalization of IgA, IgG, and IL-6 t. Their normal levels of IgA at 205, 215 and 242 (mg/dL) and the IgG at 1019, 1046 and 1346 (mg/dL) while of IL-6 at 3.60, 4.13 and 6.63 (pmol/mL) respectively. These effect were refered the parameters to became equalized with their values in the group of control animals and returned to normal.

show abstract

“…The results were in agreement with the JCPDS card. The results agreed with what was stated by [10] and [18].…”

Section: X-ray Diffraction Of Se-npssupporting

confidence: 93%

Determining the Efficacy of Selenium Nanoparticles (Se-NPs) Conjugated with Zinc and Synthesized Using Aspergillus niger on some Immunological Parameters of Induced Immunosuppressed Rats

Abd Al-Aziz,

Thalij,

Zakaria

2023

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

show abstract

“…The high content of carboxyl and hydroxyl groups makes chito-oligosaccharides more biocompatible. Furthermore, the protonation of the amino group of chito-oligosaccharides provides considerable biological activities such as antibacterial and antioxidant activity. − …”

Section: Introductionmentioning

confidence: 99%

“…14,15 Thus, natural bioactive polysaccharides are the ideal templates for SeNP stabilization due to their hydrophilic groups such as hydroxyl groups. 16 Furthermore, polysaccharide-modified SeNPs are relatively stable and cost-effective and exhibit strong antioxidant activity. 17−19 Therefore, polysaccharides can be regarded as the most promising source for the production of nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Chitosan Oligosaccharide Selenium Nanoparticles and Selenium Enrichment Evaluation and Mechanism on Soybean Sprouts

Wang

et al. 2022

ACS Agric. Sci. Technol.

View full text Add to dashboard Cite

Biofortification is an effective way to increase micronutrient levels in food crops. This study investigated selenium enrichment as a biofortification strategy in soybean sprouts. Chitosan oligosaccharide selenium nanoparticles (COS-Se NPs) were synthesized and used in soybean sprout culture to study their effects on the sprouts. The results showed that the enrichment factor value (EF) was higher when the concentration was 2.36−9.43 mg•L −1 compared with other concentrations, and the enrichment factor (EF) reached a maximum value of 0.9782 at a COS-Se NP concentration of 4.72 mg•L −1 . Translocation factors (TF radicle-hypocotyl and TF hypocotyl-cotyledon ) reached maximum values of 0.7866 and 0.9723 at 25.15 mg•L −1 and 15.09 mg•L −1 , respectively, suggesting the relationship between enrichment of nanoselenium and concentration was not proportional. Most of the organic selenium was present mainly in the protein fraction, and albumin and glutelin were the main protein-bound seleniums. The contents of protein and biomacromolecule selenium reached higher values at a COS-Se NP concentration of 2.36−9.43 mg•L −1 . Furthermore, the COS-Se NPs at 2.36−9.43 mg•L −1 concentration significantly affected the nutrient parameters in soybean sprouts. Different concentrations of COS-Se NPs were observed to have different effects on the mineral element content of the bean sprouts. In vitro digestion and dialysis experiments showed that the bioavailability of K, Mg, P, and Se was at a high level, while that of Fe and Ca was at a low level in soybean sprouts. Overall, no significant impact on the bioaccessibility of most elements was observed during the enrichment process compared to the control group. This work shows that the selenium enrichment strategy can be a potential soybean sprout production method and help solve the problem of nutritional deficiencies with selenium and reduce malnutrition.

show abstract

“…Chondroitin sulfate (CS), an anionic glycosaminoglycan derived from animal cartilage, is widely used in various biopharmaceutical applications. This Special Issue presents a theoretical study on the use of CS derived from shark cartilage as a stabilizing agent of selenium nanoparticles (SeNPs) [ 3 ]. Selenium (Se) is an essential micronutrient for human health due to its antioxidant properties, but the narrow margin between beneficial and harmful doses limits its practices in food and medicine.…”

mentioning

confidence: 99%

“…Chen et al (2022) prepared selenium-chondroitin sulfate (SeCS) via a redox reaction of sodium selenite and ascorbic acid, using shark CS as a template. SeCS possessed good storage stability and had higher antioxidant activity than SeNPs and CS [ 3 ]. Therefore, the authors proposed the application of SeCS in the prevention and mitigation of oxidative stress-related diseases.…”

mentioning

confidence: 99%

News and Updates from 2022 on Antioxidant and Anti-Inflammatory Properties of Marine Products

Vasarri

Degl’Innocenti

2022

Marine Drugs

View full text Add to dashboard Cite

show abstract

Preparation and Characterization of Nano-Selenium Decorated by Chondroitin Sulfate Derived from Shark Cartilage and Investigation on Its Antioxidant Activity

Cited by 13 publications

References 28 publications

Determining the Efficacy of Selenium Nanoparticles (Se-NPs) Conjugated with Zinc and Synthesized Using Aspergillus niger on some Immunological Parameters of Induced Immunosuppressed Rats

Determining the Efficacy of Selenium Nanoparticles (Se-NPs) Conjugated with Zinc and Synthesized Using Aspergillus niger on some Immunological Parameters of Induced Immunosuppressed Rats

Synthesis and Characterization of Chitosan Oligosaccharide Selenium Nanoparticles and Selenium Enrichment Evaluation and Mechanism on Soybean Sprouts

News and Updates from 2022 on Antioxidant and Anti-Inflammatory Properties of Marine Products

Contact Info

Product

Resources

About