Preparation and Characterization of New Substitutjed 5-Methoxy-2-Styryl-4-Pyrones

Stiplošek, Z.; Šindler‐Kulyk, Marija; Jakopcic, K.

doi:10.1080/00304949909458331

Cited by 4 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the Arbuzov reaction of 2‐(bromomethyl)‐5‐methoxy‐4 H ‐pyran‐4‐one 4 and triethyl phosphite (P(OEt) 3 ) in toluene at reflux gave phosphonate 5 in 68% isolated yield. Having the phosphonate 5 in hand, a series of (E)‐5‐methoxy‐2‐styryl‐4‐pyrones 6a , 6b , 6c , 6d , 6e , 6f , 6g , 6h , 6i , 6j was successfully synthesized by the Horner–Emmons reaction, in which the phosphonate 5 and various benzaldehydes underwent olefination reaction mediated by the base sodium hydride (NaH) in the anhydrous THF solution .…”

Section: Resultsmentioning

confidence: 99%

Synthesis of (E)‐5‐Methoxy‐2‐styryl‐4‐pyrones as Potent Growth‐Inhibitory Agents Against Hepatocellular Carcinoma Cells

Chen

Hulme

et al. 2013

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Synthesis of (E)‐5‐Methoxy‐2‐styryl‐4‐pyrones as Potent Growth‐Inhibitory Agents Against Hepatocellular Carcinoma Cells

Chen

Hulme

et al. 2013

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

ChemInform Abstract: Preparation and Characterization of New Substituted 5‐Methoxy‐2‐styryl‐4‐pyrones.

1999

View full text Add to dashboard Cite

show abstract

On the photochemical dimerization of some 5‐substituted 2‐styryl‐4‐pyrones. The effect of 5‐hydroxy‐/ 5‐methoxy‐substitution

Stiplošek

Šindler‐Kulyk

Jakopcic

et al. 2002

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

Irradiation of styryl‐4‐pyrones 1a‐1d or 2a‐2e (6‐9 × 10−3 M, methanol solution) with filtered (RAYONET photochemical reactor, 300 nm) or unfiltered uv‐light (high‐pressure mercury arc lamp) under aerobic conditions led mainly to dimeric products. Parent 5‐hydroxy‐substituted compounds 1a‐1d yielded exclusively “half‐cage” dimers 3a‐d characteristic for 4‐pyrone dimerization. 5‐Methoxy‐analogues 2a‐2e behave like typical stilbene structures and the mixture of tetrasubstituted cyclobutanes 4 and 5 accompanied with minor amount of phenanthrene‐like compound 6 were the only isolable products of the irradiation. The structure elucidation of products is based on spectral data obtained from MS, IR, 1H NMR and 13C NMR spectra applying COSY, APT, HETCOR, HMBC and NOESY techniques.

show abstract

Preparation and Characterization of New Substitutjed 5-Methoxy-2-Styryl-4-Pyrones

Cited by 4 publications

References 8 publications

Synthesis of (E)‐5‐Methoxy‐2‐styryl‐4‐pyrones as Potent Growth‐Inhibitory Agents Against Hepatocellular Carcinoma Cells

Synthesis of (E)‐5‐Methoxy‐2‐styryl‐4‐pyrones as Potent Growth‐Inhibitory Agents Against Hepatocellular Carcinoma Cells

ChemInform Abstract: Preparation and Characterization of New Substituted 5‐Methoxy‐2‐styryl‐4‐pyrones.

On the photochemical dimerization of some 5‐substituted 2‐styryl‐4‐pyrones. The effect of 5‐hydroxy‐/ 5‐methoxy‐substitution

Contact Info

Product

Resources

About