Preparation and Characterization of new Azo/Azo-Chalcone Ligands and their mixed ligands transition metal complexes with A study of Palladium Complex Anticancer Activity

Synthesis, characterization and study anticancer activity of new Azo –Chalcone with mix Ligand of some divalent metal chelate complexes

“…The FTIR spectrum of the azo-chalcone was given an absorption band at the 3433cm -1 belonging to the (OH) group of paracetamol overlapping with the (NH) group(30) and the appearance of an absorption band at 1662cm -1 due to the carbonyl (C=O) group in Paracetamol (31),absorption band at the site 1489cm -1 for the (N=N) azo group (32) , absorption bands at the 2927cm -1 and 3057cm -1 referred to the aliphatic and aromatic C-H group and an absorption band at the 1020cm -1 attributed to the (C-Br) group(31) .The spectra of chelate complexes appeared and an absorption band at 3): Some of physical properties of (L 1 ), (L 2 ), and their complexes Electronic spectra and Magnetic susceptibility UV-Visible Spectroscopy, one of the significant methods in which electronic spectral data were recorded and compared with free ligand. In this study the measurement was solvated in DMSO solvent at room temperature, where the spectrum of the ligand (azo-chalcone) appeared shows two main bands, the first one at (262) nm for the (π →π*) and band at (320) nm for the electronic transition ( n→π*) which attributed to the azo group (N=N) , this band agonized from a red shift to longer wavelengths depending on coordination with chelate metal ions (34). The table (4) includes the electronic transition of Co (II), Ni (II), Cu (II), Zn (II) and Cd (II) complexes with charge transfer transition .The value of the magnetic moment gives information about predictable coordination of the metal ion and it suggests the geometric shape of complex's .The magnetic moment value of Co(II)complex suggested an octahedral geometry with high spin state.…”