Preparation and characterization of octyl phenyl polyoxyethylene ether modified organo-montmorillonite for ibuprofen controlled release

Yan, Huiqiong; Zhang, Pan; Chen, Xiuqiong; Bao, Chaoling; Zhao, Rui; Hu, Jisen; Liu, Chang; Lin, Qiang

doi:10.1016/j.clay.2020.105519

Cited by 21 publications

(4 citation statements)

References 54 publications

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“…The use of such a drying procedure limited the aggregation of grains and the closing of meso- and macropores, because such phenomena may take place during classical drying. Organo-montmorillonite modified with nonionic octyl phenyl polyoxyethylene ether using a wet ball-milling method and then freeze-dried [ 46 ] also had a larger S BET and V tot . The increase in these parameters was related to the pulverization of the massive particles during the wet ball-milling process.…”

Section: Resultsmentioning

confidence: 99%

The Effect of Surfactant-Modified Montmorillonite on the Cross-Linking Efficiency of Polysiloxanes

Wójcik‐Bania

Matusik

2021

Materials

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Polymer–clay mineral composites are an important class of materials with various applications in the industry. Despite interesting properties of polysiloxanes, such matrices were rarely used in combination with clay minerals. Thus, for the first time, a systematic study was designed to investigate the cross-linking efficiency of polysiloxane networks in the presence of 2 wt % of organo-montmorillonite. Montmorillonite (Mt) was intercalated with six quaternary ammonium salts of the cation structure [(CH3)2R’NR]+, where R = C12, C14, C16, and R’ = methyl or benzyl substituent. The intercalation efficiency was examined by X-ray diffraction, CHN elemental analysis, and Fourier transform infrared (FTIR) spectroscopy. Textural studies have shown that the application of freezing in liquid nitrogen and freeze-drying after the intercalation increases the specific surface area and the total pore volume of organo-Mt. The polymer matrix was a poly(methylhydrosiloxane) cross-linked with two linear vinylsiloxanes of different siloxane chain lengths between end functional groups. X-ray diffraction and transmission electron microscopy studies have shown that the increase in d-spacing of organo-Mt and the benzyl substituent influence the degree of nanofillers’ exfoliation in the nanocomposites. The increase in the degree of organo-Mt exfoliation reduces the efficiency of hydrosilylation reaction monitored by FTIR. This was due to physical hindrance induced by exfoliated Mt particles.

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Section: Resultsmentioning

confidence: 99%

The Effect of Surfactant-Modified Montmorillonite on the Cross-Linking Efficiency of Polysiloxanes

Wójcik‐Bania

Matusik

2021

Materials

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“…On the basis of the IUPAC systematization, the nitrogen adsorption−desorption isotherms of Mt, Mt-HMDA, and Mt-BPEI show Type IV isotherms with the type H4 hysteresis loops. 29,30 The specific surface areas and pore volumes of Mt-HMDA and Mt-BPEI were less than those of Mt. Because the specific surface area and pore volume were positively correlated with the adsorption capacity, the amounts of adsorbed water for Mt-HMDA and Mt-BPEI were less than that of Mt.…”

Section: Resultsmentioning

confidence: 99%

Intercalation Inhibits the Surface Hydration of Sodium Montmorillonite: Experiments and Density Functional Theory Simulation

Xie

Huang

Xiao

et al. 2020

ACS Sustainable Chem. Eng.

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In order to use water-based drilling fluids to substitute for oil-based drilling fluids in the drilling industry, one of the main challenges is the inhibiting the surface hydration of clay to further develop oil and gas resources. In this work, low-molecular weight branched polyethylenimine (BPEI) and hexamethylenediamine (HMDA) as inhibitors were used to investigate the inhibitory mechanism of surface hydration on sodium montmorillonite (Mt) using isothermal adsorption, X-ray diffraction (XRD), thermogravimetric analysis (TGA), low field nuclear magnetic resonance (LF-NMR), the Brunner–Emmet–Teller (BET) technique, scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray (EDX), and density functional theory (DFT) simulations. The XRD results confirmed that HMDA and BPEI could decrease the d 001 values of hydrated Mt from 1.91 to 1.32 and 1.39 nm, respectively. These results verified that the interlamellar space of Mt-HMDA and Mt-BPEI may contain one layer of water molecules. TGA and LF-NMR analyses further confirmed that HMDA can restrict Mt to one-layer hydration, while BPEI can completely inhibit the interlayer surface hydration of Mt. The HMDA and BPEI could displace the exchangeable cations in the interlamellar space of Mt, whereas as the number of primary amine groups increased, both the displaced exchangeable cations and the inhibition performance increased. The DFT simulation results showed that, as the number of primary amine groups increased, both the adsorption energy of the inhibitor on the Mt surface and the inhibition performance increased. Finally, the mechanism of the inhibition of the clay surface hydration through intercalation adsorption was put forward. The theory and method can be helpful in designing inhibitors that completely inhibit the surface hydration of clay.

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“…Refined MMT has been studied for various common health applications, such as cosmetics [ 7 , 8 ], wound dressings [ 9 , 10 , 11 , 12 , 13 ], and anti-diarrhea medicines [ 14 ], owing to the uniform bidimensional particle shapes, high length-to-height ratios, inherent stiffness, dual charge distribution, chemical inertness, biocompatibility, and active sites on the surface [ 15 , 16 , 17 , 18 ]. The results of these studies have attracted the interest of scientists and biotechnologists since micro/nanosized materials might also exhibit the same micro/nano biological interactions because one functional dimension is outside the nanoscale range of 1 nm to 100 nm, whereas organ-modified micro/nanosized materials might have uncertain effects on micro/nanobiological interactions [ 19 , 20 , 21 , 22 ]. The material parameters included size, shape, surface chemical characteristics, and surface topological structure, whereas the biological information included signaling molecule transmission, cell internalization, tissue distribution, and organ filtration [ 23 , 24 , 25 , 26 ].…”

Section: Introductionmentioning

confidence: 99%

Toxicological Evaluation toward Refined Montmorillonite with Human Colon Associated Cells and Human Skin Associated Cells

Wang,

Jiang,

Tian

et al. 2024

JFB

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Montmorillonite has been refined to overcome uncertainties originating from different sources, which offers opportunities for addressing various health issues, e.g., cosmetics, wound dressings, and antidiarrheal medicines. Herein, three commercial montmorillonite samples were obtained from different sources and labeled M1, M2, and M3 for Ca-montmorillonite, magnesium-enriched Ca-montmorillonite, and silicon-enriched Na-montmorillonite, respectively. Commercial montmorillonite was refined via ultrasonic scission-differential centrifugation and labeled S, M, or L according to the particle sizes (small, medium, or large, respectively). The size distribution decreased from 2000 nm to 250 nm with increasing centrifugation rates from 3000 rpm to 12,000 rpm. Toxicological evaluations with human colon-associated cells and human skin-associated cells indicated that side effects were correlated with excess dosages and silica sand. These side effects were more obvious with human colon-associated cells. The microscopic interactions between micro/nanosized montmorillonite and human colon-associated cells or human skin-associated cells indicated that those interactions were correlated with the size distributions. The interactions of the M1 series with the human cells were attributed to size effects because montmorillonite with a broad size distribution was stored in the M1 series. The M2 series interactions with human cells did not seem to be correlated with size effects because large montmorillonite particles were retained after refining. The M3 series interactions with human cells were attributed to size effects because small montmorillonite particles were retained after refining. This illustrates that toxicological evaluations with refined montmorillonite must be performed in accordance with clinical medical practices.

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Preparation and characterization of octyl phenyl polyoxyethylene ether modified organo-montmorillonite for ibuprofen controlled release

Cited by 21 publications

References 54 publications

The Effect of Surfactant-Modified Montmorillonite on the Cross-Linking Efficiency of Polysiloxanes

The Effect of Surfactant-Modified Montmorillonite on the Cross-Linking Efficiency of Polysiloxanes

Intercalation Inhibits the Surface Hydration of Sodium Montmorillonite: Experiments and Density Functional Theory Simulation

Toxicological Evaluation toward Refined Montmorillonite with Human Colon Associated Cells and Human Skin Associated Cells

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