Preparation and characterization of polydimethylsiloxane/poly(vinylalcohol) coated solid phase microextraction fibers using sol–gel technology

Lopes, Alexandre Gomes; Augusto, Fábio

doi:10.1016/j.chroma.2004.05.047

Cited by 51 publications

(20 citation statements)

References 20 publications

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“…Other bands ranging from 800 to 1200 cm -1 have already been assigned to Si-O bonds from PDMS-OH. 10 These assignments are consistent with that expected from silica organically modified with aminopropyl and polydimethylsiloxane groups.…”

Section: Resultssupporting

confidence: 77%

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Solid Phase Microextraction Fibers Coated with Sol-gel Aminopropylsilica/polydimethylsiloxane: Development and Its Application to Screening of Beer Headspace

Biajoli

Augusto

2008

ANAL. SCI.

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The preparation and applicability of solid phase microextraction (SPME) fibers coated with a sol-gel organically modified silica based on 3-aminopropyltrimethoxysilane and polydimethylsiloxane (APTMS/PDMS) are described here. Micrographs of the coated fibers revealed a rugous surface; the thickness of the coating was estimated to be less than 30 mm. The APTMS/PDMS fibers were tested with synthetic samples and compared to commercial fibers for headspace SPME analysis of beer. Extraction and desorption using the APTMS/PDMS fibers were faster, which is typical for sol-gel SPME fibers. For polar and semi-polar compounds on beer headspace, the extraction efficiencies of the APTMS/PDMS fiber were superior to those of conventional fibers. The APTMS/PDMS fiber was found to be capable of extracting a broad range of analytes, including highly polar acidic species such as organic acids.

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Section: Resultssupporting

confidence: 77%

“…The sol-gel approach for the production of SPME fiber coatings started gaining attention in many research groups. Sol-gel active moieties incorporated in fiber coatings include compounds like fullerenes, 7 calixarenes, 8 cyclodextrins, 9 poly(vinyl alcohol) 10 and poly(ethylene glycol).…”

Section: Introductionmentioning

confidence: 99%

Solid Phase Microextraction Fibers Coated with Sol-gel Aminopropylsilica/polydimethylsiloxane: Development and Its Application to Screening of Beer Headspace

Biajoli

Augusto

2008

ANAL. SCI.

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“…The use of sol-gel ormosils as non-specific sorbent coatings for SPME (solid phase microextraction) fibers has been pioneered by Malik and co-workers 25 and has been extensively employed since. [26][27][28] Phenobarbital shares the actions of anticonvulsants and is effective in the management of epilepsy in subhypnotic doses. As an anticonvulsant, phenobarbital is used principally in the management of tonic-clonic and partial seizures.…”

Section: Introductionmentioning

confidence: 99%

Molecularly imprinted sol-gel silica for solid phase extraction of phenobarbital

Pilau¹,

Silva²,

Jardim³

et al. 2008

J. Braz. Chem. Soc.

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Sílica organicamente modificada e molecularmente impressa foi preparada através de um procedimento sol-gel simples, e avaliada como sorvente específico para extração em fase sólida (Solid Phase Extraction, SPE) de fenobarbital em amostras aquosas e forenses. As propriedades analíticas dessa sílica molecularmente impressa (MIS, molecularly imprinted silica) foram inicialmente avaliadas e o material determinado como específico para as espécies-alvo: o fator de impressão IF, medido como a razão entre o pico do fenobarbital em cromatogramas de MIS e NIS (sílica não-impressa) foi estimado como 58. Este valor é consideravelmente maior que aquele apresentado normalmente para sorventes de impressão convencional baseados em metacrilatos e sugere que interações não-específicas analito/sorvente são insignificantes no MIS. O material foi aplicado no isolamento de fenobarbital de amostras aquosas e plasma; limites de detecção de 10 e 62 µg mL -1 , respectivamente, foram encontrados para essas amostras.A molecularly imprinted organically modified silica was prepared through a simple sol-gel procedure, and evaluated as specific sorbent for solid-phase extraction (SPE) of phenobarbital from aqueous and forensic samples. The analytical properties of the molecularly imprinted silica (MIS, non-imprinted sílica) were initially evaluated and the MIS was found to be specific towards the target species: the imprinting factor IF, measured as the ratio between phenobarbital peak areas in the MIS and NIS chromatograms, was estimated as 58. This value is considerably higher than those usually found for conventional methacrylate-based molecularly imprinted sorbents and suggests that non-specific analyte/sorbent interactions are insignificant in the MIS. This material is applied to the isolation of phenobarbital from aqueous samples and plasma; detection limit of 10 and 62 µg mL -1 was achieved for the former samples, respectively. Keywords: molecularly imprinted silica, sol-gel, ormosils, phenobarbital, SPE IntroductionThere is a demand for sensitive, accurate and simple analytical procedures. One of the tools to achieve these goals is the incorporation of biomolecules and biologicallike processes in the methodologies. However, despite of the specificity achieved on these procedures, natural biomolecules usually are expensive and chemically unstable. Synthetic materials such as molecularly imprinted polymers (MIP) are valid alternatives to these biological matrices. Molecular imprinting was proposed by Pauling 1 as a possible mechanism for the production of antibodies by living systems. According to his model, the synthesis of antibodies was based on the use of the aggressor chemical molecules as templates. Weak intermolecular forces such as hydrogen bonding or van der Waals forces drove proper monomer units to organize themselves around the antigen. Polymerization of the organized monomers and removal of the template would render macromolecules with cavities where the template or other species with similar structure could be highly select...

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“…The PDMS/PVA sol solution was prepared as reported in ref. [21]. Briefly, 1 g OH-PDMS, 0.3 g PVA, 250 lL MTMS, 250 lL PMHS, 250 lL CH 2 Cl 2 , and 250 lL of 95% aqueous TFA were mixed in agitation.…”

Section: Preparation Of Stir Barsmentioning

confidence: 99%

Sol–gel polydimethylsiloxane/poly(vinylalcohol)‐coated stir bar sorptive extraction of organophosphorus pesticides in honey and their determination by large volume injection GC

Hu²

2008

J of Separation Science

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A PDMS/poly(vinylalcohol) (PDMS/PVA) film prepared through a sol-gel process was coated on stir bars for sorptive extraction, followed by liquid desorption and large volume injection-GC-flame photometric detector (LVI-GC-FPD) for the determination of five organophosphorus pesticides (OPPs) (phorate, fenitrothion, malathion, parathion, and quinalphos) in honey. The preparation reproducibility of PDMS/PVA-coated stir bar ranged from 4.3 to 13.4% (n = 4) in one batch, and from 6.0 to 12.6% (n = 4) in batch to batch. And one prepared stir bar can be used for more than 50 times without apparent coating loss. The significant parameters affecting stir bar sorptive extraction (SBSE) were investigated and optimized. The LODs for five OPPs ranged from 0.013 (parathion) to 0.081 microg/L (phorate) with the RSDs ranging from 5.3 to 14.2% (c = 1 microg/L, n = 6). The proposed method was successfully applied to the analysis of five OPPs in honey.

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Preparation and characterization of polydimethylsiloxane/poly(vinylalcohol) coated solid phase microextraction fibers using sol–gel technology

Cited by 51 publications

References 20 publications

Solid Phase Microextraction Fibers Coated with Sol-gel Aminopropylsilica/polydimethylsiloxane: Development and Its Application to Screening of Beer Headspace

Solid Phase Microextraction Fibers Coated with Sol-gel Aminopropylsilica/polydimethylsiloxane: Development and Its Application to Screening of Beer Headspace

Molecularly imprinted sol-gel silica for solid phase extraction of phenobarbital

Sol–gel polydimethylsiloxane/poly(vinylalcohol)‐coated stir bar sorptive extraction of organophosphorus pesticides in honey and their determination by large volume injection GC

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