Preparation and characterization of water soluble high molecular weight β-cyclodextrin-epichlorohydrin polymers

Renard, Estelle; Deratani, A.; Volet, Gisèle; Sébille, Bernard

doi:10.1016/s0014-3057(96)00123-1

Cited by 350 publications

(250 citation statements)

References 29 publications

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“…Table 1 Zimm plot of polyCD shows that it possesses a high weight-average molar mass ̅ ,which is a desirable physico-chemical characteristic for obtaining uniform fibers, as described elsewhere [35]. Previous studies have reported that the weight-average molar mass of polyCDs depends on the experimental conditions, such as the reaction time, the EP/βCD molar ratio, temperature and NaOH concentration [28]. In the present work, all of these parameters were controlled to develop a reproducible synthesis for polyCD.…”

Section: Characterization Of Cd-based Polymermentioning

confidence: 75%

Electrospun nanofibers of polyCD/PMAA polymers and their potential application as drug delivery system

Oliveira

Suárez

Rocha

et al. 2015

Materials Science and Engineering: C

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Herein, we used an electrospinning process to develop highly efficacious and hydrophobic coaxial nanofibers based on poly-cyclodextrin (polyCD) associated with poly(methacrylic acid) (PMAA) that combines polymeric and supramolecular features for modulating the release of the hydrophilic drug, propranolol hydrochloride (PROP). For this purpose, polyCD was synthesized and characterized, and its biocompatibility was assessed using fibroblast cytotoxicity tests. Moreover, the interactions between the guest PROP molecule and both polyCD and βCD were found to be spontaneous. Subsequently, PROP was encapsulated in uniaxial and coaxial polyCD/ PMAA nanofibers. A lower PROP burst effect (reduction of approximately 50%) and higher modulation were observed from the coaxial than from the uniaxial fibers. Thus, the coaxial nanofibers could potentially be a useful strategy for developing a controlled release system for hydrophilic molecules.

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Section: Characterization Of Cd-based Polymermentioning

confidence: 75%

Electrospun nanofibers of polyCD/PMAA polymers and their potential application as drug delivery system

Oliveira

Suárez

Rocha

et al. 2015

Materials Science and Engineering: C

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“…The polymer of -CD, denoted as CDE, was synthesized by copolymerization with epichlorohydrin. Details of its synthesis and structural characterization are reported elsewhere [22,23]. The polymer displays a hyperbranched architecture in which -CD molecules are modified by poly(2-hydroxypropyl)ether sequences with different lengths.…”

Section: 1mentioning

confidence: 99%

Associating Polymer Networks Based on Cyclodextrin Inclusion Compounds for Heavy Oil Recovery

Zheng

Luo

et al. 2018

Journal of Chemistry

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This work evaluates an approach to improve the enhanced heavy oil recovery performance of hydrophobic associating polymer. A polymeric system based on water-soluble hydrophobic associating polymer (WSHAP) and cyclodextrin (CD) polymer was proposed in this work. Addition of CD polymer to WSHAP forms interpolymer bridges by inclusion of CD groups with hydrophobic tails, and thereby the network structure is strengthened. The proposed system offers good viscoelasticity, pronounced shear thinning, and interesting viscosity-temperature relations. Sand pack tests indicated that the proposed system can build high resistance factor during the propagation in porous media, and its moderate adsorption phenomenon was represented by the thickness of the adsorbed layer. The relationship between effective viscosity and oil recovery increment indicated that the proposed system can significantly reduce the residual oil saturation due to the "piston-like" propagation. The overall oil recovery was raised by 5.7 and 24.5% of the original oil in place compared with WSHAP and partially hydrolyzed polyacrylamide (HPAM), respectively.

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“…Renard et al [16] established that the molar weight of these water soluble polymers depends on initial features like initial ratio (epichlorohydrin/β-CD), NaOH concentration, and reaction time. They indicated that low concentrations of NaOH promote substitution on the two sides of the CD cavity, while high NaOH concentrations result in substitution mainly on one side of the cavity.…”

Section: Network Of Polymers and Cyclodextrinsmentioning

confidence: 99%

Inclusion and Functionalization of Polymers with Cyclodextrins: Current Applications and Future Prospects

2014

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Abstract:The numerous hydroxyl groups available in cyclodextrins are active sites that can form different types of linkages. They can be crosslinked with one another, or they can be derivatized to produce monomers that can form linear or branched networks. Moreover, they can form inclusion complexes with polymers and different substrates, modifying their physicochemical properties. This review shows the different applications using polymers with cyclodextrins, either by forming inclusion complexes, ternary complexes, networks, or molecularly imprinted polymers (MIPs). On one hand, the use of cyclodextrins enhances the properties of each polymer, and on the other the use of polymers decreases the amount of cyclodextrins required in different formulations. Both cyclodextrins and polymers contribute synergistically in several applications such as pharmacological, nutritional, environmental, and other industrial fields. The use of polymers based on cyclodextrins is a low cost easy to use potential tool with great future prospects.

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Preparation and characterization of water soluble high molecular weight β-cyclodextrin-epichlorohydrin polymers

Cited by 350 publications

References 29 publications

Electrospun nanofibers of polyCD/PMAA polymers and their potential application as drug delivery system

Electrospun nanofibers of polyCD/PMAA polymers and their potential application as drug delivery system

Associating Polymer Networks Based on Cyclodextrin Inclusion Compounds for Heavy Oil Recovery

Inclusion and Functionalization of Polymers with Cyclodextrins: Current Applications and Future Prospects

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