Preparation and Colorimetric Properties of Aluminon

Smith, William Hayden; Sager, E.E.; Siewers, Iris J.

doi:10.1021/ac60035a008

Cited by 54 publications

(12 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…H 2 SO 4 ) solution. A similar procedure was already used by Smith for the preparation of 3‐carboxy 4,4′‐dihydroxy diphenyl methane from salicylic acid 16. Phenol and salicylaldehyde to trioxane ratio must be very high in order that the FDDM be formed rather than a polymeric product in acidic medium, according to Scheme .…”

Section: Resultsmentioning

confidence: 99%

Synthesis, characterization, and antimicrobial studies of newly developed metal‐chelated epoxy resins

Nishat

Ahmad

Ahamad

2006

J of Applied Polymer Sci

View full text Add to dashboard Cite

A series of novel metal-chelated epoxy resins have been synthesized by the condensation of epichlorohydrin (1-chloro-2, 3 epoxy propane) with bisphenolic metal chelates in alkaline medium. The bisphenolic chelates were initially prepared by the reaction of 3-formyl-4, 4Ј-dihydroxy diphenyl methane and diamine (ethylenediamine/ophenylenediamine) in 1:2 molar ratio and then with Cu(II), Ni(II), and Co(II) acetate. The metal-chelated epoxy resins were characterized by various instrumental techniques, such as elemental analysis, DSC and TGA, electronic, FTIR, 1 H-NMR, and 13 C-NMR spectra. The physicochemical properties, viz., epoxide equivalent weight (eq/100 g), hydroxyl value (eq/100 g), refractive index, specific gravity, and specific viscosity were measured by standard procedures. The antimicrobial activities of these chelated resins were screened against Escherichia coli, Staphylococcus aureus, Bacillius subtilis (bacteria), and Candida albicans, Mucor species (yeast) by using agar well diffusion method. All the polymeric chelates show promising antimicrobial activities. Among these polymeric chelates (ERPD)-Cu(II) shows better antimicrobial activities, which can be attributed to higher stability constant of Cu(II) chelate than others.

show abstract

Section: Resultsmentioning

confidence: 99%

Synthesis, characterization, and antimicrobial studies of newly developed metal‐chelated epoxy resins

Nishat

Ahmad

Ahamad

2006

J of Applied Polymer Sci

View full text Add to dashboard Cite

show abstract

“…Such general binding activity of ATA could be due to its anionic charge. Moreover ATA binds to and is an indicator for A13+ (Smith et al, 1949). Therefore, it might be argued that the survival promoting effects of ATA are due to either its anionic properties, chelation of ions, or binding of metals necessary for cell death to occur.…”

Section: Aurin Inhibits Dna Fragmentation and Promotes Survival Of Pcmentioning

confidence: 99%

“…However, ATA has a number of known activities in addition to nuclease inhibition, and it might be argued that one or more of these is responsible for its survival-promoting actions. Such activities include binding to a variety of cellular proteins and chelating metal ions such as AI 3+ (Bina-Stein and Tritton, 1976;Smith et al, 1949). To investigate such possibilities, we tested the actions of aufin, an analog of ATA that lacks tricarboxylic acid groups and anionic charge and that consequently would be less likely to undergo charge-based chelation of metal ions and non-specific binding to proteins.…”

Section: Ata and Aurinmentioning

confidence: 99%

Internucleosomal DNA cleavage and neuronal cell survival/death

Batistatou

Greene

1993

The Journal of Cell Biology

188

111

View full text Add to dashboard Cite

Abstract. Serum-free PC12 cell cultures have been used to study the mechanisms of neuronal death after neurotrophic factor deprivation. We previously reported that PC12 cells undergo "apoptotic" internucleosomal DNA cleavage after withdrawal of trophic support. Here, we have used a sensitive method to detect PC12 cell DNA fragmentation within three hrs of serum removal and have exploited this assay to examine several aspects regarding the mechanisms of neuronal survival/death. Major advantages of this assay are that it permits acute experiments to be performed well before other manifest signs of cell death and under conditions that cannot be applied chronically. We find that this apopotic DNA fragmentation is distinct from the random DNA degradation that occurs during necrotic death. Major observations include the following: (a) There is a good correlation between the ability of trophic substances to promote PC12 cell survival and to inhibit early DNA fragmentation. (b)Phorbol ester, an activator of PKC, acutely suppresses DNA fragmentation, but does not promote long-term survival or inhibition of endonuclease activity when applied chronically due to its downregulation of PKC. (c) Cells undergoing apoptosis within 3 h of serum withdrawal have a "commitment point" of only 1.0-1.5 h beyond which they can no longer be rescued by NGF. (d) Aurin, a non-carboxylic analog of the endonuclease inhibitor ATA, also inhibits DNA fragmentation and promotes short-term survival of PC12 cells. (e) Macromolecular synthesis is not required for DNA fragmentation or for NGF to prevent this event.(D Extracellular Ca 2÷ is not required for internucleosomal DNA cleavage caused by serum withdrawal or for suppression of this by NGF. (g) DNA fragmentation can also be detected in cultures of rat sympathetic neurons as early as 10 h after removal of NGF. As in PC12 cell cultures, this precedes morphological signs of cell death.

show abstract

“…Aluminum is being utilized to an increasing extent in the manufacture of steels for deep drawing applications. A study of methods for preparation and use of aluminon for the colorimetric determination of this element was made during the past year (80). Chenery (13) found thioglycolic acid useful in inhibiting the reaction of iron when determining aluminum colorimetrically with aluminon.…”

Section: Specific Methodsmentioning

confidence: 99%

Ferrous Metallurgy

Beeghly¹

1950

Anal. Chem.

View full text Add to dashboard Cite

PRACTICALadvances in ferrous analytical chemistry result from a correlation of available information with experience in selecting the most likely approach to solution of a specific problem. Frequently these advances are made under the compulsion of need for new or better data on experimental operations or new experimental alloys, and the chemist utilizes the store of basic information in the literature along with new reagents and tools as a basis for devising the method best suited to his requirements and the working facilities at his disposal. BASIC INFORMATION

show abstract

Preparation and Colorimetric Properties of Aluminon

Cited by 54 publications

References 17 publications

Synthesis, characterization, and antimicrobial studies of newly developed metal‐chelated epoxy resins

Synthesis, characterization, and antimicrobial studies of newly developed metal‐chelated epoxy resins

Internucleosomal DNA cleavage and neuronal cell survival/death

Ferrous Metallurgy

Contact Info

Product

Resources

About