Preparation and dehydration of α-perfluorobutyl carbinols

Nucleophilic Perfluoroalkylation of Aldehydes, Ketones, Imines, Disulfides, and Diselenides

“…1-Perfluoro- n -butylcyclohexanol (3b) was prepared in the same manner, and its proton and fluorine NMR spectra were also identical to those previously reported. , …”

Modified natural substances—fluorinated and fluoroalkylated monosaccharides and inositols

“…The radical addition of 1-halogeno-perfluoroalkanes to p-bonds using sodium dithionite as an initiator is one of the most convenient methods to link perfluoroalkyl chains to organic substrates [42][43][44]; for other methods of initiation see ref. [45][46][47] and papers cited therein.…”

Squaramide/Li+-Catalyzed Direct SN1-Type Reaction of Vinyl Triflates with Difluoroenoxysilanes through Vinyl Cations

“…In fact, E1 eliminations of alcohols exhibiting a vicinal gem-difluoro substitution pattern are difficult to achieve since the corresponding carbocations would be destabilized by the electron-withdrawing ability of the fluorine atoms. 14 E2 approaches are also known to be difficult, 15 which give credit to the present methodology compared to classical aldol/dehydration ap-proaches. Finally, we tested the reaction of phenylacetylene, which could form after elimination of TfOH from 1a (eq 4).…”