Preparation and deployment of indigenous 125I-seeds for the treatment of prostate cancer: Dawn of prostate brachytherapy in India

Saxena, Sandeep K.; Mukherjee, Archana; Kumar, Yogendra; Ram, Ramu; Tapase, A. S.; Anand, Vivek; Dash, Ashutosh

doi:10.1007/s10967-014-3521-3

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…Despite availability of low-dose-rate (LDR) BT seeds in India [ 13 ], it may not gain preference over HDR in our country. In the question of choosing between LDR-BT and HDR-BT, 80 respondents withheld their answer because of lack of experience in prostate BT.…”

Section: Resultsmentioning

confidence: 99%

Current status and future readiness of Indian radiation oncologists to embrace prostate high-dose-rate brachytherapy: An Indian Brachytherapy Society survey

Banerjee,

Sarkar,

Mahantshetty

et al. 2023

jcb

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Purpose This survey aimed to understand the practice pattern and attitude of Indian doctors towards prostate brachytherapy. Material and methods A 21-point questionnaire was designed in Google form and sent to radiation oncologists practicing in India, using texts, mails, and social media. Responses were collated, and descriptive statistical analysis was performed. Results A total of 212 radiation oncologists from 136 centers responded to the survey questionnaire, with majority (66%) being post-specialty training > 6 years. We found that about 44.3% ( n = 94) of respondents do not practice interstitial brachytherapy for any site, and majority (83.3%, n = 175) do not practice high-dose-rate (HDR) prostate brachytherapy. Only 2.8% ( n = 6) of doctors preferred boost by brachytherapy compared with 38.1% ( n = 80) of respondents, who favored stereotactic body radiation therapy (SBRT) boost. When asked about the indication of HDR prostate brachytherapy in Indian setting, 32.5% ( n = 67) of respondents favored monotherapy, 46.1% ( n = 95) of oncologists thought boost as a good indication, and 21.4% ( n = 44) preferred re-irradiation/salvage setting. The most cited reason for prostate brachytherapy not being popularly practiced in India was lack of training (84.8%, n = 179). It was also noted that out of 80 respondents who practiced SBRT for prostate boost, 37 would prefer HDR brachytherapy boost if given adequate training and facilities. Conclusions The present survey provided insight on practice of prostate brachytherapy in India. It is evident that majority of radiation oncologists do not practice HDR prostate brachytherapy due to lack of training and infrastructure. Indian physicians are willing to learn and start prostate brachytherapy procedures if dedicated training and workshops are organized.

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Section: Resultsmentioning

confidence: 99%

Current status and future readiness of Indian radiation oncologists to embrace prostate high-dose-rate brachytherapy: An Indian Brachytherapy Society survey

Banerjee,

Sarkar,

Mahantshetty

et al. 2023

jcb

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Development and deployment of 141Ce fiducial marker sources for supplementing nuclear diagnostic procedures

Saxena

Kumar

Bamankar

et al. 2020

J Radioanal Nucl Chem

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Deposition of Iodine-125 on Silver Supports of Microsources for Prostate Cancer Brachytherapy

et al. 2022

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A method of iodine-125 deposition on a surface of microsource silver supports for brachytherapy of prostate cancer was reported, which includes preparing the support surface by sequentially treating them with nitric acid and thiourea solutions, followed by chlorination of the support surface with a chlorinating agent to form silver chloride on the support surface, and substitution of chlorine atoms for 125I atoms by placing supports containin silver chloride on the surface in a solution with 125I ions to create a 125I layer on the support surface. The method described allows fixing 125I on supports with a low activity distribution on each activity-carrying support.

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Preparation and deployment of indigenous 125I-seeds for the treatment of prostate cancer: Dawn of prostate brachytherapy in India

Cited by 3 publications

References 15 publications

Current status and future readiness of Indian radiation oncologists to embrace prostate high-dose-rate brachytherapy: An Indian Brachytherapy Society survey

Current status and future readiness of Indian radiation oncologists to embrace prostate high-dose-rate brachytherapy: An Indian Brachytherapy Society survey

Development and deployment of 141Ce fiducial marker sources for supplementing nuclear diagnostic procedures

Deposition of Iodine-125 on Silver Supports of Microsources for Prostate Cancer Brachytherapy

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