Preparation and disinfection properties of graphene oxide/trichloroisocyanuric acid disinfectant

Abstract

In this study, graphene oxide (GO) was first prepared by the modified Hummer method. Then, the GO/trichloroisocyanuric acid (TCCA) composite was prepared by loading TCCA into GO with the blending method. X-ray diffraction, scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy and atomic force microscopy were used to characterize the composite. The results showed that TCCA was successfully loaded on the surface of GO or intercalated among GO layers. Next, the antibacterial performance of the composite against Escherichia coli and Staphylococcus aureus was tested by the 96-well plate assay. A bactericidal kinetic curve, bacterial inhibition tests, and the mechanism of bacterial inhibition is discussed. The results showed that the minimum inhibitory concentration of the GO/TCCA composite (GO:TCCA ratio = 1:50) was 327.5 µg/mL against E. coli and 655 µg/mL against S. aureus. At the minimum inhibitory concentration, the inhibition rate of the GO/TCCA composite exceeded 99.46% against E. coli and 99.17% against S. aureus. The bactericidal kinetic curves indicate that the GO/TCCA composite has an excellent bactericidal effect against E. coli and S. aureus.

Coronavirus disease 2019: Repeated immersion of chlorine-containing disinfectants has adverse effects on goggles

“…Therefore, its development and research have received attention from various countries. Recently, Jiang et al made a novel nan-efficient disinfectant by loading trichloroisocyanuric acid into graphene oxide with the blending method (14). As front-line personnel at COVID-19, goggles disinfected with chlorine-containing disinfectants are often used due to necessary PPE scare.…”