Preparation and evaluation of chitosan biocompatible electronic skin

Lin, Yu-Hsin; Kang, Pei-Leun; Wang, Xin; Yen, Ching-Shu; Hwang, Lain-Chyr; Liu, Jen‐Tsai; Chang, Shwu Jen

doi:10.1016/j.compind.2018.03.040

Cited by 22 publications

(13 citation statements)

References 23 publications

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“…Chemical modification can not only improve the physical and chemical properties of chitosan, it can also retain the unique properties of chitosan and expand the application range of chitosan derivatives. Modified chitosan derivatives have better biocompatibility, bioactivity, anticancer, and antiviral pharmacological effects, including the ability to induce erythrocyte aggregation, promote platelet activation, and activate complement systems other than that of chitosan [8][9][10][11][12][13]. At present, chitosan derivatives have been widely used in both medical materials and biomedicine.…”

Section: Introductionmentioning

confidence: 99%

Chitosan Derivatives and Their Application in Biomedicine

Wang

Meng

et al. 2020

IJMS

649

326

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Chitosan is a product of the deacetylation of chitin, which is widely found in nature. Chitosan is insoluble in water and most organic solvents, which seriously limits both its application scope and applicable fields. However, chitosan contains active functional groups that are liable to chemical reactions; thus, chitosan derivatives can be obtained through the chemical modification of chitosan. The modification of chitosan has been an important aspect of chitosan research, showing a better solubility, pH-sensitive targeting, an increased number of delivery systems, etc. This review summarizes the modification of chitosan by acylation, carboxylation, alkylation, and quaternization in order to improve the water solubility, pH sensitivity, and the targeting of chitosan derivatives. The applications of chitosan derivatives in the antibacterial, sustained slowly release, targeting, and delivery system fields are also described. Chitosan derivatives will have a large impact and show potential in biomedicine for the development of drugs in future.

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Section: Introductionmentioning

confidence: 99%

Chitosan Derivatives and Their Application in Biomedicine

Wang

Meng

et al. 2020

IJMS

649

326

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“…Among the natural polymers, like cellulose, liver sugar, starch and chitin used in biomedical applications [ 57 , 58 , 59 ], chitosan has attracted attention because possesses antibacterial, antiviral, and anticancer effects. In addition, relevant chemical and physical modifications of chitosan give derivatives with desirable biodegradability, biocompatibility, bioactivity and non-toxicity properties [ 60 , 61 , 62 , 63 , 64 ]. Chitosan flat structures contribute to biomedical applications, especially for their ability to accelerate wound healing and optimize drug delivery.…”

Section: Applications Of Chitosan Flat Structuresmentioning

confidence: 99%

Ionotropic Gelation of Chitosan Flat Structures and Potential Applications

et al. 2021

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The capability of some polymers, such as chitosan, to form low cost gels under mild conditions is of great application interest. Ionotropic gelation of chitosan has been used predominantly for the preparation of gel beads for biomedical application. Only in the last few years has the use of this method been extended to the fabrication of chitosan-based flat structures. Herein, after an initial analysis of the major applications of chitosan flat membranes and films and their usual methods of synthesis, the process of ionotropic gelation of chitosan and some recently proposed novel procedures for the synthesis of flat structures are presented.

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“…In addition to the abovementioned polymers, there are some other insulated biodegradable or biocompatible polymers that can be used in electronics, such as starch [98,99], chitosan [100,101], albumen [102], and poly (glycerol-co-sebacate) (PGS) [103], which will not be introduced in detail.…”

Section: Biodegradable and Biocompatible Polymersmentioning

confidence: 99%

Application of Biodegradable and Biocompatible Nanocomposites in Electronics: Current Status and Future Directions

et al. 2019

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With the continuous increase in the production of electronic devices, large amounts of electronic waste (E-waste) are routinely being discarded into the environment. This causes serious environmental and ecological problems because of the non-degradable polymers, released hazardous chemicals, and toxic heavy metals. The appearance of biodegradable polymers, which can be degraded or dissolved into the surrounding environment with no pollution, is promising for effectively relieving the environmental burden. Additionally, biodegradable polymers are usually biocompatible, which enables electronics to be used in implantable biomedical applications. However, for some specific application requirements, such as flexibility, electric conductivity, dielectric property, gas and water vapor barrier, most biodegradable polymers are inadequate. Recent research has focused on the preparation of nanocomposites by incorporating nanofillers into biopolymers, so as to endow them with functional characteristics, while simultaneously maintaining effective biodegradability and biocompatibility. As such, bionanocomposites have broad application prospects in electronic devices. In this paper, emergent biodegradable and biocompatible polymers used as insulators or (semi)conductors are first reviewed, followed by biodegradable and biocompatible nanocomposites applied in electronics as substrates, (semi)conductors and dielectrics, as well as electronic packaging, which is highlighted with specific examples. To finish, future directions of the biodegradable and biocompatible nanocomposites, as well as the challenges, that must be overcome are discussed.

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Preparation and evaluation of chitosan biocompatible electronic skin

Cited by 22 publications

References 23 publications

Chitosan Derivatives and Their Application in Biomedicine

Chitosan Derivatives and Their Application in Biomedicine

Ionotropic Gelation of Chitosan Flat Structures and Potential Applications

Application of Biodegradable and Biocompatible Nanocomposites in Electronics: Current Status and Future Directions

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