2019
DOI: 10.1208/s12249-019-1343-x
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Preparation and Evaluation of Mosapride Citrate Dual-Release Dry Suspension

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Cited by 5 publications
(3 citation statements)
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“…In addition, the peaks at 1394 and 1319 cm −1 were attributed to –OH and C–O stretching vibrations for the LHPC polymer [ 35 ]. The absence of changes in the main frequencies of MX and LHPC for the physical mixture spectrum indicated the lack of MX–polymer interaction [ 34 , 36 ]. However, both solid dispersions showed a slight shift for the vibration peaks at 3383 and 3389 cm −1 , which were related to –OH stretching bands for SD − MX:LHPC (1:1) and SD − MX:LHPC (1:2.5), respectively.…”
Section: Resultsmentioning
confidence: 99%
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“…In addition, the peaks at 1394 and 1319 cm −1 were attributed to –OH and C–O stretching vibrations for the LHPC polymer [ 35 ]. The absence of changes in the main frequencies of MX and LHPC for the physical mixture spectrum indicated the lack of MX–polymer interaction [ 34 , 36 ]. However, both solid dispersions showed a slight shift for the vibration peaks at 3383 and 3389 cm −1 , which were related to –OH stretching bands for SD − MX:LHPC (1:1) and SD − MX:LHPC (1:2.5), respectively.…”
Section: Resultsmentioning
confidence: 99%
“…Therefore, these changes detected in the solid dispersions SD − MX:LHPC (1:1) and SD − MX:LHPC (1:2.5) could be attributed to the hydrogen bonding interaction. This interaction was produced among the hydroxyl moieties from MX and the –OH and C–O moieties from LHPC [ 36 ]. The following bands at 3285, 2909, 2893, and 1520 cm −1 , related to N–H, C–H, and C=N stretching vibrations from LHPC polymer and MX, did not change.…”
Section: Resultsmentioning
confidence: 99%
“…Suspension is a disperse system in which the internal phase is dispersed uniformly throughout the external phase, and the internal phase consists of insoluble solid particles with the aid of single or combination of suspending agents (Zhang et al 2019). The dry suspension has the characteristics of convenient transportation and good stability, and is suitable for patients who have difficulty in swallowing (Liu et al 2019). In our study, a series of excipients were used to improve the solubility of resveratrol; the final content of resveratrol in the formulation was 2.93%, which was in line with the relevant standards.…”
Section: Discussionmentioning
confidence: 99%