Preparation and functional evaluation of agarose derivatives

Abstract

A facile microwave‐assisted one‐pot synthesis of sodium carboxymethylagarose and calcium carboxymethylagarose from Gracilaria dura agarose (Ag) has been described. The process is user friendly, and the highest degree of substitution was obtained within 15 min compared with the conventional method, which requires more than 3 h. Solubility and gelling behavior of the modified Ag products were found to be dependent on degree of substitution of the products. The characterizations were done by using Fourier transform infrared spectroscopy, 1H‐ and 13C‐nuclear magnetic resonance spectroscopy, thermogravimetric analysis, scanning electron microscopy, Inductively coupled plasma spectrophotometry (ICP), rheology, conductometer analysis, and DNA gel electrophoresis. These agarose derivatives were easily soluble in water and exhibited low thermal hysteresis, improved conductivity, and improved the DNA resolution ability of the parent G. dura Ag hydrogels. These hydrogels may have potential applications in the areas including electrochemical devices, microbiology, biomedical, and pharmaceuticals fields. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40630.

Thermal, mechanical, and morphological characterization of biobased thermoplastic starch from agricultural waste/polypropylene blends

“…The amylose-to-amylopectin ratio can influence the properties of the biobased materials. It is reported that amylose-rich materials are preferred because they show better thermal stability, superior strength, and lower water absorption than amylopectinrich materials [4][5][6]. In this study, the starch-containing agricultural waste had a lower amylose content than normal native starch, even as low as only 1% amylose, with the remainder being amylopectin.…”

Exorbitant Drug Loading of Metformin and Sitagliptin in Mucoadhesive Buccal Tablet: In Vitro and In Vivo Characterization in Healthy Volunteers

“…The results depict that, at such a ratio of polymers of AG, sustainability in drug release was not achieved and showed a poor release retardant effect. This might be due to the fact that AG possesses weak hydrophilic forces in powder form [44], while PVP, the hydrophilic polymer, did not impart the required results with the release of both drugs, and the tablets diminished completely after 2 h of sampling. Consequently, the drugs dissolute with a faster release from eroded matrix [45].…”

Seaweed‐derived polymer‐based blue‐emitting C‐dots: synthesis, characterization and evaluation for iron sensing

“…CMA was synthesized from seaweed polysaccharide agar extracted from Gracilaria edulis using a previously reported method (with high DS) 25 . Sodium hydroxide and isopropyl alcohol were purchased from Thermo Fisher Scientific India Pvt Ltd. Metal (lithium, mercury, arsenic, cadmium, rubidium, chromium, copper, cobalt, strontium, zinc, magnesium and nickel) ions (perchlorate salts) were purchased from Alfa Aesar.…”