Preparation and pH with Antibacterial Evaluation of Nano Calcium Oxide Based Intracanal Medicament from Natural Products : An In Vivo Study

Taher, Rajaa; Chakmakchi, Makdad; Taqa, Amer A.

doi:10.12816/0060713

Cited by 2 publications

(1 citation statement)

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“…In addition, the usage of CaO can be used in dental applications due to its biocompatibility [8]. A recent study also shows that usage of CaO in root canal treated teeth was successful due to good ability to adhere to tooth structure combined with low solubility and also good mechanical properties [9]. There is also a report that addition of CaO to stabilize zirconia shows relatively good mechanical properties [10,11].…”

Section: Introductionmentioning

confidence: 99%

Effect of Sintering Temperature on the Properties of Calcia-Stabilized Zirconia (Ca-SZ) Bioceramics

Johari

Ab‐Ghani

Shariff

et al. 2022

SSP

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This paper highlights the study on effect of sintering temperature on the morphologies and compressive strength of zirconia ceramics doped with calcium oxide (CaO) as stabiliser to enhance the zirconia structure undergo sudden phase transformation. CaO reportedly has good stability in cubic phase at all temperature, which open up a new possibility for new material to evolve for zirconia ceramic dental application. CaO synthesis from calcium nitrate tetrahydrate (Ca(NO3)2.4H2O) is used as metal precursor to produce Calcia-Sabilized Zirconia (Ca-SZ). 8 wt. % of Ca(NO3)2.4H2O and 92 wt. % of zirconium oxide (ZrO2) mixed and stirred together with ethanol as solvent and sintered at temperatures 1200, 1300 and 1400°C. Surface morphologies are investigated by Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Spectroscopy (EDX) element analysis, X-ray Diffraction (XRD) for composition studies, as well as compressive strength to figure out the mechanical properties of Ca-SZ sample. Increment in sintering temperature enhance the surface morphologies, the phase of Ca-SZ become intensified and transformed from monoclinic to tetragonal ZrO2 also flexural strength increases as well. The compressive strength recorded the highest value of 4537 MPa for Ca-SZ at temperature of 1400°C. The optimal temperature of Ca-SZ suitable for dental application was 1400°C due to the good morphologies and mechanical properties suitable for teeth restoration. The development of Ca-SZ can establish a pathway as an alternative material for dental applications.

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Section: Introductionmentioning

confidence: 99%

Effect of Sintering Temperature on the Properties of Calcia-Stabilized Zirconia (Ca-SZ) Bioceramics

Johari

Ab‐Ghani

Shariff

et al. 2022

SSP

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In Vitro Evaluation of the Influence of Biosynthesized Calcium Oxide Nanoparticles on the Antibacterial Activity, pH, Microleakage and Cytotoxicity of Conventional Intracanal Medicaments

Kazi,

Parvez,

Asghar

et al. 2024

IJMS

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Intracanal medicaments are an important adjunct to the effective disinfection of the root canal system. However, conventional intracanal medicaments do not provide adequate protection against Enterococcus faecalis, which is the organism of interest in many cases of root canal failures. This study aimed to evaluate the influence of biosynthesized calcium oxide nanoparticles (CaO NPs) on the antibacterial activity, pH, microleakage and cytotoxicity of intracanal medicaments. CaO NPs were biosynthesized by the direct thermal decomposition of eggshells (EGS) and the reduction of calcium nitrate with papaya leaf extract (PLE). These nanoparticles were mixed with a proprietary calcium hydroxide powder in 10% and 25% (w/w) concentrations and blended in analytical-grade coconut oil to formulate the experimental medicaments. These were then evaluated for antibacterial activity, pH, microleakage and cytotoxicity at 1 day, 7 days and 15 days. A proprietary calcium hydroxide paste formulation (MX) was used as the control. Means and standard deviations were calculated and analyzed using repeated-measures ANOVA for pH and three-way ANOVA for the antibacterial effect, microleakage and cytotoxicity, followed by LSD post hoc analysis. Significant antibacterial activity was noted against Enterococcus faecalis at all times, with zones of inhibition (ZOI) up to 19.60 ± 2.30 mm. pH levels up to 13.13 ± 0.35 were observed for the experimental groups. Microleakage remained comparable to the control, while cytotoxicity was not observed in any of the groups at any time. Intracanal medicaments formulated with 10% and 25% (w/w) of biosynthesized CaO NPs could be promising candidates for the disinfection of the root canal system compared to conventional counterparts.

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Preparation and pH with Antibacterial Evaluation of Nano Calcium Oxide Based Intracanal Medicament from Natural Products : An In Vivo Study

Cited by 2 publications

References 0 publications

Effect of Sintering Temperature on the Properties of Calcia-Stabilized Zirconia (Ca-SZ) Bioceramics

Effect of Sintering Temperature on the Properties of Calcia-Stabilized Zirconia (Ca-SZ) Bioceramics

In Vitro Evaluation of the Influence of Biosynthesized Calcium Oxide Nanoparticles on the Antibacterial Activity, pH, Microleakage and Cytotoxicity of Conventional Intracanal Medicaments

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