Preparation and properties of magnetic Fe3O4–chitosan nanoparticles

Li, Guiyin; Jiang, Yuren; Huang, Kelong; Ding, Ping; Chen, Jie

doi:10.1016/j.jallcom.2007.11.100

Cited by 483 publications

(205 citation statements)

References 19 publications

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“…The results of XRD patterns of D. radiodurans show three sharp peaks with a decrease in the intensity of the these peaks for un-loaded biosorbent after exposing the bacteria to Pb (II) and Cd (II), which could explain the immobilization process. This is in agreement with the results reported in the literatures of [23][24][25]. And this may suggest that Pb (II) and Cd (II) immobilized on surface of D. radiodurans [26].…”

Section: Xrdsupporting

confidence: 93%

Biosorption of some Heavy Metals by Deinococcus radiodurans Isolated from Soil in Basra Governorate-Iraq

Jaafar¹,

A²

2016

J Bioremed Biodeg

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IntroductionBioremediation is a natural process which depends on bacteria, fungi, and plants to alternating pollutants as these organisms carry out their normal life functions. Thus, bioremediation offers a substitute tool to destroy or reduce the harmful pollutants through biological activity with an effective cost. In the early 1980s, certain microorganisms were found to accumulate metallic elements at a high capacity [1,2].There are a lot of studies about the bioremediation ability of D. radiodurans and its genetic engineering, for cleaning up heavy metals in nuclear waste contaminated sites [3][4][5][6][7]. The development of bioremediation strategies using Deinococcus spp is therefore vital for the cleanup of contaminated site with radioactive waste. Additional advantages of deinococci are that they are vegetative, easily cultured, and nonpathogenic. As these sites rarely contaminated by a single chemical, it is necessary to bio remediating strain to be multi resistant to various toxic agents. The present work describes the use of a combination of spectroscopic and microscopic methods to characterize the heavy metals around the cells of bacterial strains isolated from extreme habitats as well as to elucidate the interaction mechanisms of these bacteria with these metals. Materials and Methods Source of bacterial isolateThe tested isolates, D. radiodurans used in this study was isolated previously from the Um -Qasr district, south of Basra city-Iraq. The isolate was identified by biochemical tests and sequencing 16S rRNA gene and comparing the sequences online with GenBank database (www.ncbi.nlm.nih.gov). Biosorption experimentThe equilibrium, kinetics data of the biosorbent D. radiodurans were obtained by performing batch experiments AbstractThe bacterium Deinococcus radiodurans has been isolated from Basra soil. On the basis of morphological, biochemical, 16S rRNA gene sequencing and phylogeny analysis, the isolates were authentically identified as D. radiodurans. The biosorption capabilities of D. radiodurans for cadmium (Cd +2 ) and lead (Pb +2 ) were monitored at different concentrations and contact times. The characterization of heavy metals around the cells of bacterial strains was observed using the Fourier Transform Infrared (FT-IR) spectrophotometer, X-ray powder diffraction analysis (XRD) and transmission electron microscope (TEM).preparation UATR). This analysis was done in the Chemistry department, University Putra Malaysia.

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Section: Xrdsupporting

confidence: 93%

Biosorption of some Heavy Metals by Deinococcus radiodurans Isolated from Soil in Basra Governorate-Iraq

Jaafar¹,

A²

2016

J Bioremed Biodeg

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“…Restricting the size to below that of the single domain size ensures super paramagnetic property, this coupled with chemical stability [6] make IONPs extremely promising for biomedical applications. Inorganic core of iron oxide, such as magnetite (Fe 3 O 4 ), and maghemite (γ-Fe 2 O 3 ) coated with a polymer such as chitosan [7] dextran [8], poly (ethylene glycol) (PEG) [9] and poly(ethylenimine) (PEI) [10], have been reported earlier. Another method for forming monolayers is by self-assembly ligand exchange for noble metal nanoparticles, where, the thiol groups attach strongly to the surface.…”

Section: Introductionmentioning

confidence: 90%

Biomimetically Synthesized Aqueous Ferrofluids Having Antibacterial and Anticancer Properties

Sheikh¹,

Vohra²,

Verma³

et al. 2015

MSA

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Synthesis of functional iron oxide nanoparticles, well dispersed in aqueous fluids still remains a challenge as its stability requires a delicate balance between electrostatic and magnetic interactions. Templated synthesis using biomolecules is useful because the biomolecules have their unique arrangement in aqueous systems that enhance stability, commonly called "biomimetic synthesis". We have developed a one-pot in-situ, low energy process for the synthesis of highly monodispersed, Collagen Functionalized Ferrofluids (CFF) as a templating agent in an aqueous medium. The nanoparticles so obtained were characterized by X-ray diffraction (

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“…The FNPs show one stage weight loss which occurred at 286°C, which is corresponding to the loss of residual water with 4.1 % weight loss (Fig. 3a) [32]. Thermogravimetric curve of free drug (PE) shows two main thermal stages.…”

Section: Thermogravimetric Analysismentioning

confidence: 98%

“…Therefore, to find a new nanocomposite for the treatment of hypertension, iron oxide nanoparticles can be selected due to low toxicity, low cost of production, ability to immobilize biological materials on their surfaces, potential for direct biodegradable, and suitable for surface modifications. To minimize the aggregation of iron oxide nanoparticles (FNPs), which causes due to dipole-dipole attractions between particles [31,32], PEG was coated on the surface of FNPs to create FNPs-PEG. Then, perindopril erbumine (PE), a long-acting angiotensinconverting enzyme inhibitor, which prevents various medical conditions indicating reduced systolic and diastolic BP in patients with mild-to-moderate hypertension, congestive heart failure and diabetic nephropathy [33,34] was loaded on the surface of FNPs-PEG and formed a new FPEGPE nanocomposite.…”

Section: Introductionmentioning

confidence: 99%

Controlled-release formulation of perindopril erbumine loaded PEG-coated magnetite nanoparticles for biomedical applications

et al. 2014

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Iron oxide nanoparticles (FNPs) were synthesized due to low toxicity and their ability to immobilize biological materials on their surfaces by the coprecipitation of iron salts in ammonia hydroxide followed by coating it with polyethylene glycol (PEG) to minimize the aggregation of iron oxide nanoparticles and enhance the effect of nanoparticles for biological applications. Then, the FNPs-PEG was loaded with perindopril erbumine (PE), an antihypertensive compound to form a new nanocomposite (FPEGPE). Transmission electron microscopy results showed that there are no significant differences between the sizes of FNPs and FPEGPE nanocomposite. The existence of PEG-PE was supported by the FTIR and TGA analyses. The PE loading (10.3 %) and the release profiles from FPEGPE nanocomposite were estimated using ultraviolet-visible spectroscopy which showed that up to 60.8 and 83.1 % of the adsorbed drug was released in 4223 and 1231 min at pH 7.4 and 4.8, respectively. However, the release of PE was completed very fast from a physical mixture (FNPs-PEG-PE) after 5 and 7 min at pH 4.8 and 7.4, respectively, which reveals that the release of PE from the physical mixture is not in the sustained-release manner. Cytotoxicity study showed that free PE presented slightly higher toxicity than the FNPs and FPEGPE nanocomposite. Therefore, the decrease toxicity against mouse normal fibroblast (3T3) cell lines prospective of this nanocomposite together with controlled-release behavior provided evidence of the possible beneficial biological activities of this new nanocomposite for nanopharmaceutical applications for both oral and non-oral routes.

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Preparation and properties of magnetic Fe3O4–chitosan nanoparticles

Cited by 483 publications

References 19 publications

Biosorption of some Heavy Metals by Deinococcus radiodurans Isolated from Soil in Basra Governorate-Iraq

Biosorption of some Heavy Metals by Deinococcus radiodurans Isolated from Soil in Basra Governorate-Iraq

Biomimetically Synthesized Aqueous Ferrofluids Having Antibacterial and Anticancer Properties

Controlled-release formulation of perindopril erbumine loaded PEG-coated magnetite nanoparticles for biomedical applications

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