Preparation and Visible Light Polymerization of Triethyleneglycol Acrylate Methacrylate

Saimi, Y.; Ishihara, Kazuhíko; Nakabayashi, Nobuo

doi:10.1295/polymj.24.357

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…Thus, it is possible that the network structure of the PMPC50 hydrogel was more heterogeneous than that of the PAPC50 hydrogel. It was previously reported that the methacrylic group in triethylene glycol acrylate was polymerized in advance compared to the acrylic group [30], which is consistent with our results.…”

Section: Synthesis and Characterization Of Polymer Hydrogels Containi...supporting

confidence: 93%

Preparation and Characterization of Acrylic and Methacrylic Phospholipid-Mimetic Polymer Hydrogels and Their Applications in Optical Tissue Clearing

Dei,

Ishihara,

Matsumoto

et al. 2024

Polymers

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The 2-methacryloyloxyethyl phosphorylcholine (MPC) polymers are mimetic to phospholipids, being widely used as biocompatible polymers. In our previous study, MPC polymer hydrogels proved more effective for optical tissue clearing compared to acrylamide (AAm) polymer hydrogels. In the present study, 2-acryloyloxyethyl phosphorylcholine (APC) was synthesized and employed to create hydrogels for a comparative analysis with methacrylic MPC-based hydrogels. APC, an acrylic monomer, was copolymerized with AAm in a similar reactivity. In contrast, MPC, as a methacrylic monomer, demonstrated higher copolymerization reactivity than AAm, leading to a spontaneously delayed two-step polymerization behavior. This suggests that the polymer sequences and network structures became heterogeneous when both methacrylic and acrylic monomers, as well as crosslinkers, were present in the copolymerization system. The molecular weight of the APC polymers was considerably smaller than that of the MPC polymers due to the formation of mid-chain radicals and subsequent β-scission during polymerization. The swelling ratios in water and strain sweep profiles of hydrogels prepared using acrylic and methacrylic compounds differed from those of hydrogels prepared using only acrylic compounds. This implies that copolymerization reactivity influences the polymer network structures and crosslinking density in addition to the copolymer composition. APC-based hydrogels are effective for the optical clearing of tumor tissues and are applicable to both passive and electrophoretic methods.

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Section: Synthesis and Characterization Of Polymer Hydrogels Containi...supporting

confidence: 93%

Preparation and Characterization of Acrylic and Methacrylic Phospholipid-Mimetic Polymer Hydrogels and Their Applications in Optical Tissue Clearing

Dei,

Ishihara,

Matsumoto

et al. 2024

Polymers

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“…TREGMA was synthesized in two steps, as referred to in the literature16, 17 (see Scheme ). Firstly, MAA (86 g, 1 mol) and hydroquinone monomethyl (0.06 g) were added in a 250‐mL four‐necked flask equipped with a thermometer, an HCl‐absorbing equipment, a drop funnel, and a mechanical stirring paddle.…”

Section: Methodsmentioning

confidence: 99%

Deswelling comparison of temperature‐sensitive poly(N‐isopropylacrylamide) microgels containing functional OH groups with different hydrophilic long side chains

Zhao

et al. 2005

J Polym Sci B Polym Phys

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Two monomers containing functional OH groups with different hydrophilic long side chains (viz., triethyleneglycol methacrylate (TREGMA) and polyethyleneglycol methacrylate (PEGMA)) were selected to modify the swelling/deswelling behavior of poly(N‐isopropylacrylamide) (pNIPAM) microgels. Dynamic scattering technique, turbidimetric method, and differential scanning calorimetry (DSC) were employed to investigate the deswelling behavior of the microgels. Experimental results show that the two series of microgels are identical in that incorporation of hydrophilic chains containing OH groups causes the volume‐phase transition temperature (VPTT) of pNIPAM microgels to shift to higher temperature; the more hydrophilic the side chains, the more the VPTTs shift. Although PEGMA are more effective in elevating the VPTTs of pNIPAM microgels than TREGMA, p(NIPAM‐co‐TREGMA) microgels show better deswelling properties than p(NIPAM‐co‐PEGMA) microgels, i.e., they have much larger deswelling ratios (α) and display less continuous volume‐phase transition. The VPTTs of the modified microgels can be modulated to well close to the normal body temperature of human beings. These characteristics along with the functional OH groups they contain make the microgels competitive candidates for biomaterials. © 2005 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 43: 3575–3583, 2005

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The preparation and characterization of co-polymer microgels with transition temperature at or near physiological values

Xing

2006

Polym. Bull.

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Preparation and Visible Light Polymerization of Triethyleneglycol Acrylate Methacrylate

Cited by 4 publications

References 5 publications

Preparation and Characterization of Acrylic and Methacrylic Phospholipid-Mimetic Polymer Hydrogels and Their Applications in Optical Tissue Clearing

Preparation and Characterization of Acrylic and Methacrylic Phospholipid-Mimetic Polymer Hydrogels and Their Applications in Optical Tissue Clearing

Deswelling comparison of temperature‐sensitive poly(N‐isopropylacrylamide) microgels containing functional OH groups with different hydrophilic long side chains

The preparation and characterization of co-polymer microgels with transition temperature at or near physiological values

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