Preparation, characterization and application of organic–inorganic hybrid ractopamine multi-template molecularly imprinted capillary monolithic column

He, Juan; Fang, Guozhen; Deng, Qiling; Wang, Shuo

doi:10.1016/j.aca.2011.02.056

Cited by 48 publications

(40 citation statements)

References 18 publications

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“…In addition, the effects of electroosmotic flow (EOF) and selectivity were also studied. 502 Owing to the advantages of simple column preparation, no bubble formation and stable EOF application, opentubular CEC (OT-CEC)-based MIP columns are potential tools for the specific recognition of enantiomers among the various forms used in CEC. 503 Moon et al used an OT-CEC column with a monolithic MIP layer for simultaneous separation and characterization of phospholipid (PL) molecular structures by electrospray ionization-tandem mass spectrometry (ESI-MS/MS).…”

Section: Monolithic Column Materials For Chromatographymentioning

confidence: 99%

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Molecular imprinting: perspectives and applications

et al. 2016

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a Molecular imprinting technology (MIT), often described as a method of making a molecular lock to match a molecular key, is a technique for the creation of molecularly imprinted polymers (MIPs) with tailor-made binding sites complementary to the template molecules in shape, size and functional groups. Owing to their unique features of structure predictability, recognition specificity and application universality, MIPs have found a wide range of applications in various fields. Herein, we propose to comprehensively review the recent advances in molecular imprinting including versatile perspectives and applications, concerning novel preparation technologies and strategies of MIT, and highlight the applications of MIPs. The fundamentals of MIPs involving essential elements, preparation procedures and characterization methods are briefly outlined.Smart MIT for MIPs is especially highlighted including ingenious MIT (surface imprinting, nanoimprinting, etc.), special strategies of MIT (dummy imprinting, segment imprinting, etc.) and stimuli-responsive MIT (single/dual/ multi-responsive technology). By virtue of smart MIT, new formatted MIPs gain popularity for versatile applications, including sample pretreatment/chromatographic separation (solid phase extraction, monolithic column chromatography, etc.) and chemical/biological sensing (electrochemical sensing, fluorescence sensing, etc.). Finally, we propose the remaining challenges and future perspectives to accelerate the development of MIT, and to utilize it for further developing versatile MIPs with a wide range of applications (650 references).

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Section: Monolithic Column Materials For Chromatographymentioning

confidence: 99%

“…502 The prepared imprinting capillary monolithic column was evaluated with CEC for the recognition of ractopamine. In addition, the effects of electroosmotic flow (EOF) and selectivity were also studied.…”

Section: Monolithic Column Materials For Chromatographymentioning

confidence: 99%

Molecular imprinting: perspectives and applications

et al. 2016

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“…Hence, NHSG hybrids can subtly increase the selectivity of the hybrid monolithic MIPs [103]. Similarly, a MIP hybrid monolith was also prepared by using acrylamide and ␥-MAPS as precursors, methanol and toluene as porogenic solvents, AIBN as initiator, as well as four isomers of ractopamine as multitemplate molecule [104]. The imprinted hybrid monolith had good selectivity for four isomers of ractopamine, and four isomers of ractopamine could be separated completely in CEC under the optimal conditions.…”

Section: Microscale Separationmentioning

confidence: 99%

Recent advances in preparation and application of hybrid organic‐silica monolithic capillary columns

Lin

Zhang

et al. 2012

Electrophoresis

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Hybrid organic-silica monolithic columns, regarded as a second generation of silica-based monoliths, have received much interest due to their unique properties over the pure silicabased monoliths. This review mainly focuses on development in the fields of preparation of hybrid monolithic columns in a capillary and their application for CEC and capillary liquid chromatography separation, as well as for sample pretreatment of solid-phase microextraction and immobilized enzyme reactor since July 2010. The preparation approaches are comprehensively summarized with three routes: (i) general sol-gel process using trialkoxysilanes and tetraalkoxysilanes as coprecursors; (ii) "one-pot" process of alkoxysilanes and organic monomers concomitantly proceeding sol-gel chemistry and free radical polymerization; and (iii) other polymerization approaches of organic monomers containing silanes. The modification of hybrid monoliths containing reactive groups to acquire the desired surface functionality is also described.

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“…According to He et al, 31 the permeability of MIP columns can be divided into following three groups with the pressure at 1 MPa: better permeability if the mobile phase flows out in 30 s, good permeability if it takes 30 s-1 min, and poor permeability if it takes more than 1 min. The results are illustrated in Table I.…”

Section: Preparation Of Mip Monolithic Columnsmentioning

confidence: 99%

“…It controls the speed and direction of the sample movement, and also affects the separation efficiency and reproducibility. 31 In this study, thiourea was used to characterize the EOF of the prepared MIP monolithic columns. Voltage is one of the most important factors for controlling the speed and direction of EOF.…”

Section: Eof Of the Mip Monolithic Columnsmentioning

confidence: 99%

Synthesis and Evaluation of Organic–Inorganic Hybrid Molecularly Imprinted Monolith Column for Selective Recognition of Acephate and Phosphamidon in Vegetables

Wang

Zhang

et al. 2015

Adv Polym Technol

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ABSTRACT:In this study, a molecularly imprinted capillary monolithic column that can recognize the acephate and phosphamidon was synthesized by the molecular imprinting technique combined with a nonhydrolytic sol-gel process using intermediate 4-(dimethoxyphosphorothioylamino)butanoic acid as the template molecule. The resulting material was characterized by scanning electron microscopy and Fourier transform infrared spectroscopy. The potential of the prepared imprinted monolithic columns used as the stationary phase for capillary electrochromatography (CEC) was evaluated. The effects of operating voltage, pH, and acetonitrile content on the electroosmotic flow of the imprinted monolithic columns were evaluated in CEC. Under optimal conditions, the cucumber and lettuce samples spiked with acephate and phosphamidon were extracted and analyzed by this method with satisfactory recoveries ranging from 79.7 to 94.4%. The relative standard deviation for five replicates of 0.1 mg/L mixed solution of acephate and phosphamidon was in the range of 2.7-4.6%. C

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Preparation, characterization and application of organic–inorganic hybrid ractopamine multi-template molecularly imprinted capillary monolithic column

Cited by 48 publications

References 18 publications

Molecular imprinting: perspectives and applications

Molecular imprinting: perspectives and applications

Recent advances in preparation and application of hybrid organic‐silica monolithic capillary columns

Synthesis and Evaluation of Organic–Inorganic Hybrid Molecularly Imprinted Monolith Column for Selective Recognition of Acephate and Phosphamidon in Vegetables

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