Preparation for oxidative stress under hypoxia and metabolic depression: Revisiting the proposal two decades later

Osmoregulation, bioenergetics and oxidative stress in coastal marine invertebrates: raising the questions for future research

“…many shallow coastal invertebrates, which are mainly sessile or have low motility and are thus unable to escape from such conditions), to prepare adequate mechanisms to counteract the pro-oxidant conditions of arousal and re-oxygenation. When facing hypoxia, freezing, starvation or other environmental constraints inducing metabolic arrest, tolerant species are indeed capable of 'preparing for oxidative stress' (POS) (Hermes-Lima et al, 2015, 1998. This requires such organisms to increase their antioxidant defenses before triggering metabolic shutdown in order to counteract the burst of ROS generated upon reperfusion.…”

“…Russell and Cotter, 2015), although mainly in plants (Carmody et al, 2016;Suzuki et al, 2012). As reviewed by Hermes-Lima et al (2015), there is considerable indirect evidence supporting the role of ROS (and products of biomolecule oxidation) in activating transcription factors in animals, leading to antioxidant upregulation. Regarding salinity changes, in human renal cells exposed to high salinity stress, for example, ROS are required for the transactivation of specific transcription factors leading to the transcription of osmoprotective genes (Zhou et al, 2005).…”

“…However, before decreasing metabolic rates, some tolerant species/tissues or specialized cells may upregulate antioxidant defenses, a behavior that has been interpreted as a preparation for the oxidative stress (free radical burst) occurring upon recovery of standard metabolic rates and tissue reoxygenation. As reviewed by Hermes-Lima et al (2015), these processes are suggested to be directly (hormetic pathway) or indirectly mediated by ROS formation (via lipid electrophiles derived from ROS peroxidation of lipids), through the activation of transcription factors leading to the upregulation of protective mechanisms. Solid arrows represent well-described processes, while dashed arrows indicate those pathways that are less well understood.…”

Monitoring yeast mitochondria with peroxiredoxin-based redox probes: the influence of oxygen and glucose availability

“…It is likely that the agar substrate provided enough glucose to support increased NADPH production throughout the hypoxic and reoxygenation phases. In addition, hypoxic conditions may also lead to the upregulation of anti-oxidative enzymes [20].…”

Are antioxidant capacity and oxidative damage related to biological and autecological characteristics in aquatic insects?

“…A large number of environmental factors can induce oxidative stress in animals, including: oxygen (Hetz and Bradley 2005;Lushachack et al, 2005;Storey and Storey, 2010;Costantini, 2014;Hermes-Lima et al, 2015), temperature (Laurette et al, 2011;Jena et al, 2013) and feeding habits (Barbehenn, 2002(Barbehenn, , 2003Kim et al, 2007;Martínez-Ál-varez et al, 2005;Sanz et al, 2010) are directly related to ROS production (Ahmad, 1995). Oxidative stress is a strong evolutionary and ecological force (Costantini et al, 2010;Costantini, 2014).…”