Preparation, in vitro and in vivo evaluation of a novel mitiglinide microemulsions

Wang, Miaomiao; Li, Hanghang; Yang, Wenzhi

doi:10.1016/j.jsps.2023.101919

Cited by 1 publication

(1 citation statement)

References 35 publications

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“…For microemulsion systems, DLS primarily measures the droplet size information of micelles within the microemulsion system, including the hydrodynamic diameter [ 86 ], Particle Dispersion Index (PDI) [ 87 ], relaxation time [ 68 ], etc. It is also used to investigate behaviors such as droplet diffusion and coalescence under different conditions [ 77 ], analyzing the impact of different times or temperatures on system stability.…”

Section: Microemulsion Characterization Techniquesmentioning

confidence: 99%

Advancements in Characterization Techniques for Microemulsions: From Molecular Insights to Macroscopic Phenomena

Li,

Qu,

Liu

et al. 2024

Molecules

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Microemulsions are thermodynamically stable, optically isotropic, transparent, or semi-transparent mixed solutions composed of two immiscible solvents stabilized by amphiphilic solutes. This comprehensive review explores state-of-the-art techniques for characterizing microemulsions, which are versatile solutions essential across various industries, such as pharmaceuticals, food, and petroleum. This article delves into spectroscopic methods, nuclear magnetic resonance, small-angle scattering, dynamic light scattering, conductometry, zeta potential analysis, cryo-electron microscopy, refractive index measurement, and differential scanning calorimetry, examining each technique’s strengths, limitations, and potential applications. Emphasizing the necessity of a multi-technique approach for a thorough understanding, it underscores the importance of integrating diverse analytical methods to unravel microemulsion structures from molecular to macroscopic scales. This synthesis provides a roadmap for researchers and practitioners, fostering advancements in microemulsion science and its wide-ranging industrial applications.

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