“…Kimura and co-workers report a stereoselective 1,5phenyl migration on several imidazolols upon addition of base in DMSO, producing 5,5-diarylated imidazol-4-ones (ee > 90%). 102 In nature, the pinacol rearrangement is used to convert 2′-deoxyguanosine to a spiroimidazolone. 103 This reaction was found to occur naturally through single-electron oxidation under basic conditions ( pH > 8) and can also take place in acetic acid with m-chloroperbenzoic acid (mCPBA) or dimethyldioxirane (DMDO).…”