Preparation of a high‐performance magnetic molecularly imprinted sensor for SERS detection of cyfluthrin in river

Abstract

A novel magnetic molecularly imprinted sensor (Fe 3 O 4 /GO/Ag-MIPs) was successfully synthesized. Combining with the technique of surface-enhanced Raman scattering (SERS), it could be applied to detect cyfluthrin (LC). Herein, GO and Ag particles were anchored on the surface of the Fe 3 O 4 @SiO 2 to obtain the composite (Fe 3 O 4 /GO/Ag), which was prepared as a SERS substrate. Then, the Fe 3 O 4 /GO/Ag-MIPs (FGA-MIPs) prepared by precipitation polymerization was evaluated as the SERS imprinted sensor for selective detection of LC from aqueous medium. The morphology and structural properties of FGA-MIPs were characterized by a series of modern analysis measurements. The results proved that FGA-MIPs possessed wonderful magnetic separation, sensitive SERS detection, and selectivity. Under optimal conditions, it exhibited a good linear relationship (R 2 = 0.9926) between the Raman shift (at 1,004 cm −1 ) and the concentration of LC among 10 −3 -10 −8 mol/L, and the limit of detection was 10 −8 mol/L. Meanwhile, the selective experiment indicated that this material owned specific selectivity to the template molecules. Thus, the result of this experiment demonstrated that the FGA-MIPs was a highly sensitive and selective sensor material in the field of LC detection, and it provided a new approach to other residual pyrethroid detection in the environment water.

Recent Advances in the Recognition Elements of Sensors to Detect Pyrethroids in Food: A Review

“…The composite structure material improves the functionality and selectivity of the SERS substrate, enhances the SERS performance of Ag particles, and degrades the templates adsorbed on its surface. Wang et al [ 72 ] synthesized Fe 3 O 4 /GO/Ag-MIPs (FGA-MIPs) and combined SERS technology to form an FGA-MIP/SERS-imprinted sensor that shows selectivity, good magnetic separation, and the sensitive detection of λ-cyhalothrin in water. This provides a new method for the determination of pyrethroid pesticides in aquatic environments.…”

Molecular-Imprinting-Based Surface-Enhanced Raman Scattering Sensors

“…82,84,85 Therefore, extraction and purification can be finished in one step, which is very beneficial for quantitative detection in the presence of matrix interferences. 86 Although the stimuli-responsive imprinting strategy makes an influential contribution to intelligent detection, limited types of SR-MIP-SERS sensors have been reported with only thermoresponsive and magnetic responsive ones available. Therefore, it is in high demand to construct new types of SR-MIP-SERS sensors, such as pH-responsive, photoresponsive, and multiresponsive ones, and apply them in drug delivery, life science, and other fields.…”

Point-of-Care Diagnostics: Molecularly Imprinted Polymers and Nanomaterials for Enhanced Biosensor Selectivity and Transduction

“…MIP-based biosensors are also routinely developed for the (108). Soil samples were tested for the herbicide diuron with a MIP-based HPLC strategy (59).…”

“…While there exists a paucity of reports on true magnetic biosensors utilizing MIPs for analyte binding, there are many MIP reports that leverage MNPs for sample heterogenization, thereby enhancing analyte concentration (99,151). SERS biodetection is advanced through a nanocomposite comprised of an MNP core for sample purification as well as GO layer and AgNPs for signal enhancement (108). This nanocomposite was further functionalized with an MIP via precipitation polymerization of the functional monomer acrylamide within the shell of the construct (Fig.…”