Preparation of a New Sol-Gel Molecularly Imprinted Polymer with Isatin Template for an On-Line SolidPhase Extraction of HMF from Fruit Juice Samples

Abstract

The present paper introduces a new MIS polymer by combining the imprinting technique with a sol-gel process utilizing isatin as a dummy template. The synthesized sorbent was used to develop a sensitive and rapid online SPE technique for the selective extraction Abstract 5-hydroxymethylfurfural (HMF) is an aromatic compound that is an admitted indicator of reduced quality in different foodstuffs.Here, a novel, sensitive, and simple online solid-phase extraction (SPE) based on a molecularly imprinted sol-gel polymer (MIS) coupled to an HPLC-UV was designed and developed for the extraction and determination of HMF. Under optimum conditions, good linearity was achieved from 0.03 to 0.45 µg ml -1 with relative standard deviations (RSDs) below 5.17%. The Limit of detection (LOD) was 0.023 µg ml -1 , and the recoveries of spiked real samples were more than 97%. The experimental results demonstrated that the proposed procedure is not to be affected by the matrix interfaces and can be successfully utilized for the routine analysis of HMF in different samples.

Introduction of a Zn-based metal–organic framework @ biomass porous activated carbon as a high-sensitive coating for a stainless steel SPME fiber: application to the simultaneous analysis of nonsteroidal anti-inflammatory drugs

“…All the samples were collected in cleaned glass vials and transported to the laboratory in a cooling box. The collected samples were stored in the refrigerator at 4 °C until analysis [ 31 ]. The water samples were applied directly for the DI-SPME procedure after filtering through a Whatman Fi filter paper (150 mm), without any other pre-treatment.…”