Preparation of alginate and chitosan nanoparticles using a new reverse micellar system

Kafshgari, Morteza Hasanzadeh; Khorram, Mohammad; Mansouri, Mohsen; Samimi, Abdolreza; Osfouri, Shahriar

doi:10.1007/s13726-011-0010-1

Cited by 61 publications

(19 citation statements)

References 36 publications

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“…o velikosti nanometrů (1-10 nm) obsahující mikroskopická polární jádra. Hydrofilní sloučeniny, jako jsou biomolekuly, jsou tedy solubilizovány uvnitř polárního jádra reverzních micel a jsou stabilizovány v organickém rozpouštědle vrstvou pláště povrchově aktivních látek, která je chrání před denaturací vlivem organické fázi (21). Nanočástice chitosanu mohou být připraveny například za použití reverzního micelárního systému složeného z cetrimoniumbromidu jako povrchově aktivní látky a izooktanu jako rozpouštědla.…”

Section: ) Metoda Reverzních Micelunclassified

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Chitosan - Prototype Polymer Nanoparticles With Transport Capacity

Kubelková¹,

Frydrychová²,

Pejchal³

2018

Mil. Med. Sci. Lett.

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Section: ) Metoda Reverzních Micelunclassified

“…Chitosan je polyanion, zatímco cetrimoniumbromid je kationtové, povrchově aktivní činidlo. V rámci podobného systému mohou být také porovnány účinky elektrostatické interakce mezi chitosanem a povrchově aktivním činidlem (16,21).…”

Section: ) Metoda Reverzních Micelunclassified

Chitosan - Prototype Polymer Nanoparticles With Transport Capacity

Kubelková¹,

Frydrychová²,

Pejchal³

2018

Mil. Med. Sci. Lett.

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“…Dynamics equation is based on the two-film theory, thus the suitability of using this model to reverse micelle system can be obtained by rearranging Eqs. (7)(8)(9)(10):…”

Section: Mass Transfer Model For Backward Extractionmentioning

confidence: 99%

Kinetics of Protein Extraction in Reverse Micelle

Guo

Chen

Yang

et al. 2015

International Journal of Food Properties

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Sodium bis (2-ethylhexyl) sulfosuccinate (AOT)-sodium dodecyl sulfate (SDS)/isooctane-octanol reverse micelle extraction was tested an efficient and effective approach to separate peanut protein from full-fat peanut powder. Here, important kinetic factors including pH, ion strength, and temperature were studied during reverse micelle backward extraction. The extraction conditions were obtained by response surface experiments as follows: pH 7.5, ion concentration 1.1 mol/L at temperature 35 • C. Under these optimum extraction conditions, the extraction rate of protein reached 79.03%. A model on the kinetic partitioning of peanut protein was also developed. The backward extraction in this reverse micelle system was controlled by interfacial resistance instead of diffusion resistance in reverse micelle and aqueous phase with the total mass transfer rate of 0.8×10 −5 m 3 ·s −1 . A two-film theory may be the mechanism for flat interface. Results of mass transfer process are helpful for creating an reverse micelle extraction process, and used for purification of peanut proteins, promoting the development of food industry.

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“…Different approaches have been used to produce CS nanoparticles. These include ionotropic gelation [13,14], spray drying [15], water-in-oil emulsion cross-linking [16], reverse micelle formation [17,18], emulsion-droplet coalescence [19,20], nanoprecipitation [21] and by a self-assembling mechanism [22,23].…”

Section: Introductionmentioning

confidence: 99%

Chitosan Based Self-assembled Nanoparticles in Drug Delivery

Quiñones

Peniche

Péniche

2018

Preprint

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Chitosan is a cationic polysaccharide usually obtained by alkaline deacetylation of chitin poly(N-acetylglucosamine). It is biocompatible, biodegradable, mucoadhesive and non-toxic. These excellent biological properties make chitosan a good candidate for a platform in developing drug delivery systems having improved biodistribution, increased specificity and sensitivity, and reduced pharmacological toxicity. In particular, chitosan nanoparticles are found to be appropriate for non-invasive routes of drug administration: oral, nasal, pulmonary and ocular routes. These applications are facilitated by the absorption-enhancing effect of chitosan. Many procedures for obtaining chitosan nanoparticles have been proposed. Particularly, the introduction of hydrophobic moieties into chitosan molecules by grafting to generate a hydrophobic-hydrophilic balance promoting self-assembly is a current and appealing approach. The grafting agent can be a hydrophobic moiety forming micelles that can entrap lipophilic drugs or it can be the drug itself. Another suitable way to generate self-assembled chitosan nanoparticles is through the formation of polyelectrolyte complexes with polyanions. This paper reviews the main approaches for preparing chitosan nanoparticles by self-assembly through both procedures and illustrates the state of the art of their application in drug delivery.

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Preparation of alginate and chitosan nanoparticles using a new reverse micellar system

Cited by 61 publications

References 36 publications

Chitosan - Prototype Polymer Nanoparticles With Transport Capacity

Chitosan - Prototype Polymer Nanoparticles With Transport Capacity

Kinetics of Protein Extraction in Reverse Micelle

Chitosan Based Self-assembled Nanoparticles in Drug Delivery

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