Preparation of alka-2,4-dienylsilanes and 3-cyclopropylprop-2-enylsilanes by the titanocene(II)-promoted reaction of 2,4-bis(phenylthio)but-3-enylsilanes

Applications of stoichiometric transition metal complexes in organic synthesis

“…27 Takeda has continued using vinyl sulfides as precursors to organotitanium species. 28 The resultant titanium carbene species can then be used to react with carbonyl compounds, or to form cyclopropanes by reactions with alkenes (Scheme 12). A closely related reaction has been achieved in an intramolecular sense using bis(phenylthio)alkanoates.…”

Synthetic methodologies for carbo-substituted conjugated dienes

“…result in the formation of a new double bond. Instead of the thioacetals 204, 1,3-diphenylthioalk-1-enes 205 (R 1 = SPh) 217 can be used in the reaction (they are produced from a,b-enals under conditions of acetalisation with monothiols). In the case of non-branched dienes (R 2 = R 4 = H), the proportion of E,E-isomer exceeds 87%.…”

The Society for Cardiovascular Angiography and Interventions' 27th Annual Scientific Sessions

“…Although Binger et al reported the preparation of 3,3‐disubstituted 2‐propenylidenetitanocenes by the reaction of 3,3‐disubstituted cyclopropenes with Cp 2 Ti(PMe 3 ) 2 ,46 the present procedure is apparently more advantageous because the precursors are readily available by thioacetalization of α,β‐unsaturated aldehydes or alkylation of 1,3‐bis(phenylthio)‐1‐propene. The trialkylsilyl group‐substituted carbene complex 45 , for instance, was prepared from the bissulfide 46 and employed for the synthesis of cyclopropyl group‐substituted allylsilane 47 (Scheme ) 47…”