Preparation of Chitosan-Coated Poly(L-Lactic Acid) Fibers for Suture Threads

Abstract

Poly(L-lactic acid) (PLA) is a biodegradable fiber, and a promising material for use in biomedical applications. However, its hydrophobicity, low hydrolyzability, and poor cell adhesion can be problematic in some cases; consequently, the development of improved PLA-based materials is required. In this study, chitosan-coated (CS-coated) PLA was prepared by plasma treatment and the layer-by-layer (LBL) method. Plasma treatment prior to CS coating effectively hydrophilized and activated the PLA surface. The LBL method was used to increase the number of CS and sodium alginate (SA) coating layers by electrostatically superposing alternating anionic and cationic polymers. The prepared fibers were characterized by tensile testing, scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), nitrogen analysis and degradation testing, which revealed that the 100 W plasma treatment for 60 s was optimum, and that plasma treatment and the LBL method effectively coated CS onto the PLA fibers. The existence or not of a coating on the PLA fiber did not appear to influence the degradation of the fiber, which is ascribable to the extremely thin coating, as evidenced by nitrogen analysis and SEM. The CS-coated PLA fibers were prepared without damaging the PLA surface and can be used in biomaterial applications such as suture threads.

Crystallization behavior analysis and reducing thermal shrinkage of poly(lactic acid) miscibilized with poly(butylene succinate) film for food packaging

“…The in situ chemically modified PLA with PBS chains was traced by a Kratos Axis Ultra DLD X‐ray photoelectron spectroscope (XPS). The binding‐energy range of 0–1000 eV was acquired to investigate the C1s (300–276.9 eV), consisting of three overlapping peaks: hydrocarbon main chain (CH/CC, C) at 285.0 eV, ether (COC) at 286.5 eV, and ester (OCO, COO) at 289.0 eV 28,29 . PLA chemically modified with PBS by bifunctional SA was quantified in terms of COO/C intensity ratio, according to Equation (). …”

Potencial Uso De Nanomateriales Combinados Con Ácido Poliláctico (Pla) en Prótesis Ortopédicas: Una Revisión

“…El PLA presenta baja resistencia mecánica, hidrolizabilidad y mala adherencia celular, por lo que podría causar no sólo fractura de la prótesis, sino infecciones en el organismo. Para su uso en exoprótesis se emplea un recubrimiento de silicona médica (Komoto et al, 2018). La nanotecnología permite manipular estructuras a nanoescala, creando materiales más resistentes utilizados en prótesis, implantes, ingeniería de tejidos, componentes de órganos artificiales, entre otros (Mediforum, 2016).…”

Degradation of hybrid material l,d-PLA : 5CB : SWCN under the influence of neutral, acidic, and alkaline environments

“…In recent years, poly(lactic acid) (PLA), the most commercially used bioplastic in the world, 3 is of great interest as a material for the production of biomedical materials and devices, such as implantable scaffolds, saturated threads, 4,5 micro- and nanoparticles, 6,7 and due to its hydrolytic degradation (compost degradation) also to remove non-toxic by-products in costly and multi-step industrial processes. 8–10…”

“…1 The specic recycling conditions for biodegradable materials are crucial. 2 In recent years, poly(lactic acid) (PLA), the most commercially used bioplastic in the world, 3 is of great interest as a material for the production of biomedical materials and devices, such as implantable scaffolds, saturated threads, 4,5 micro-and nanoparticles, 6,7 and due to its hydrolytic degradation (compost degradation) also to remove non-toxic by-products in costly and multi-step industrial processes. [8][9][10] It is important to understand the degradation process of biodegradable polymers when designing new materials and compositions that would retain their properties for a desired period of time and could be recycled quickly and efficiently.…”