This session is a continuation of Session 1. A number of methods detailing the synthesis of tritiated compounds as well as a discussion on the handling of tritium on a multi-Curie scale are presented. In addition, the descriptions of a number of preparations of individual isotopically labelled compounds are detailed. Abstract: Tritium-labeled compounds are synthesized frequently in our group in order to assess metabolism. Tritium is the label of choice because these compounds can be synthesized rapidly in most circumstances. Tritium gas and tritiated water are common label sources, in addition to other commercially available tritiating reagents. This paper will focus on recent uses of sodium borotritide, [ 3 H]methyl nosylate, and iridium catalysts with tritium gas or tritiated water in our lab.Keywords: tritium; sodium borotritide; [ 3 H]methyl nosylate; iridium catalysts; tritium gas; tritiated waterIntroduction: A number of tritium-labeled compounds are synthesized each year in our lab using a variety of approaches. Because of the need for rapid turn-around, simple labeled starting materials are used. This paper will explore four methods that we commonly use in order to label compounds with tritium. These methods include: 1) [