The harsh operating conditions of the oxygen evolution reaction (OER) in water electrolysis severely degrade the activity and stability of the electrocatalysts due to elemental leaching or particle agglomeration. Therefore, it is crucial to incorporate support materials that effectively immobilize catalyst particles for developing efficient OER catalysts. This review aims to highlight the role of MXene as a support material to improve the performance of OER catalysts. First, the extended OER mechanism is briefly described in terms of the effect of MXene support on OER catalysts. Then, various synthesis methods of MXene and catalyst‐MXene compounds are introduced, and important properties of MXene that are beneficial to improve OER performances are discussed. The electrocatalytic results of the enhanced OER catalysts due to the effective MXene support are also summarized. Finally, future challenges and prospects are proposed for utilizing MXene as an excellent support material for various electrocatalysis.