Preparation of degraded alginate as a pH-dependent release matrix for spray-dried iron and its encapsulation performances

Wardhani, Dyah Hesti; Ulya, Hana Nikma; Rahmawati, Aulia; Sugiarto, Thio V.K.; Kumoro, Andri Cahyo; Aryanti, Nita

doi:10.1016/j.fbio.2021.101002

Cited by 15 publications

(11 citation statements)

References 46 publications

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“…It was remarkable to note that with high content of sodium alginate, the percentage of degradation behavior is superior. Sodium alginate has high solubility in water, as suggested by previous literature of Wardhani et al [35]. This is also in agreement with swelling behavior reported in Figure 5.…”

Section: Resultssupporting

confidence: 92%

Utilization of freeze thaw process for polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel composite

et al. 2022

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Polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel was successfully prepared by freeze thaw process. Without crosslinking agent, hydrogel was formed by using 3, 5 and 7 consecutive cycles of freeze thaw. Hydrogel can be formed by hydrogen bonding formation between OH-group of sodium alginate and polyvinyl alcohol throughout network. Scanning electron microscope reported that microstructure of hydrogel was well packed. The interconnect porosity was also observed. Differential scanning calorimetry exhibited that two exothermic peaks at temperature of 110℃ and 225℃ were observed due to evaporation of water molecule and melting temperature of hydrogel, respectively. The swelling behavior was rapidly increased within initial stage and then it was dimensionally stable. With low sodium alginate content, tensile strength was slightly superior, whereas low in vitro degradation behavior was observed. It was remarkable to note that polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel exhibited outstanding properties for being as a medical material.

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Section: Resultssupporting

confidence: 92%

Utilization of freeze thaw process for polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel composite

et al. 2022

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“…It was remarkable to note that with high content of sodium alginate, the percentage of degradation behavior is superior. Sodium alginate has high solubility in water, as suggested by previous literature of Wardhani et al [29]. This is also in agreement with swelling behavior reported in Figure 5.…”

Section: Resultssupporting

confidence: 92%

Utilization of Freeze Thaw Process for Sodium Alginate and Polyvinyl Alcohol-Based Hydrogel Composite

Muangsri

Chuysinuan

Thanyacharoen

et al. 2022

Preprint

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Sodium alginate and poly vinyl alcohol-based hydrogel was successfully prepared by freeze thaw process. Without crosslinking agent, hydrogel was formed by using 3, 5 and 7 consecutive cycles of freeze thaw. Hydrogel can be formed by hydrogen bonding formation between OH-group of sodium alginate and poly vinyl alcohol throughout network. Scanning electron microscope reported that microstructure of hydrogel was well packed. The interconnect porosity was also observed. Differential scanning calorimetry exhibited that two exothermic peaks at temperature of 110ºC and 225ºC were observed due to evaporation of water molecule and melting temperature of hydrogel, respectively. The swelling behavior was rapidly increased within initial stage and then it was dimensionally stable. With low sodium alginate content, tensile strength was slightly superior, whereas low in vitro degradation behavior was observed. It was remarkable to note that sodium alginate and poly vinyl alcohol-based hydrogel exhibited outstanding properties for being as a medical material.

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“…Stability of iron-whey protein-isolated fibrils nanocomposites and iron nanoparticles Fe (II) ions are easily oxidised to Fe (III) ions in the environment, which reduces their bioavailability (Wardhani et al, 2021). The storage stability of Fe-FibWPI nanocomposites and Fe-Nano was evaluated by analysing the content of Fe (II) ions after storage at various conditions (Fig.…”

Section: Characterisation Of Iron-whey Protein-isolated Fibrils Nanoc...mentioning

confidence: 99%

Preparation of a novel and stable iron fortifier: self‐assembled iron‐whey protein isolate fibrils nanocomposites

Zeng

Leng

Yang

et al. 2022

Int J of Food Sci Tech

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Iron deficiency anaemia (IDA) is a major global public health problem and iron fortification of foods has been recognised as the most cost-effective prevention strategy. However, traditional iron fortificants are easily oxidised and have poor colloidal stability. Herein, we took advantages of whey protein-isolated (WPI) amyloid fibrils and developed a stable and effective iron-WPI fibrils (Fe-FibWPI) nanocomposite for iron fortification. Compared with native WPI, the antioxidant activity of WPI fibrils was significantly improved after 8 h incubation at 90 °C and pH 2.0. Importantly, the degree of fibrillation and fibril concentration influenced iron reducibility. Therefore, we utilised WPI fibrils as anti-oxidising nanocarriers to form Fe-FibWPI nanocomposites. The Fe-FibWPI showed high dispersibility compared with iron nanoparticles (Fe-Nano). Further, the in vitro bioavailability of iron was significantly higher in the Fe-FibWPI at various storage conditions than that in the Fe-Nano. Moreover, the iron-WPI fibrils could be processed into liquid, gel and powder forms, which will broaden their application. Fe-FibWPI nanocomposites have the potential to develop as iron fortificants in IDA management.

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Preparation of degraded alginate as a pH-dependent release matrix for spray-dried iron and its encapsulation performances

Cited by 15 publications

References 46 publications

Utilization of freeze thaw process for polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel composite

Utilization of freeze thaw process for polyvinyl alcohol/sodium alginate (PVA/SA) hydrogel composite

Utilization of Freeze Thaw Process for Sodium Alginate and Polyvinyl Alcohol-Based Hydrogel Composite

Preparation of a novel and stable iron fortifier: self‐assembled iron‐whey protein isolate fibrils nanocomposites

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