Preparation of Electrochemical Sensor for Paracetamol Detection Based on a New Piperazine Substituted Triazole-Coumarin Hybrid Doped PEDOT Modified Flexible HOPG Electrode

Abstract

Electrochemical determination of paracetamol (PC) using an electrode prepared by a one step electropolymerization of the new coumarin-based Schiff base-doped PEDOT conductive polymer on a highly oriented pyrolytic graphite (HOPG) substrate is reported. The electrodes were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, and X-ray diffraction analysis. The possible interference effects of ascorbic acid, uric acid, dopamine, glucose, and caffeine were investigated by chronoamperometry in the presence of paracetamol. The sensor (PEDOT-MC1/HOPG-10 Scan) has a high sensitivity to paracetamol, with a limit of detection (LOD) of 0.312 µM and a RSD % of 1.22 (S/N = 3). In addition, real sample analyzes were performed on pharmaceutical samples for PC determination using the prepared sensor (PEDOT-MC1/HOPG-10 Scan).

A Tripartite Composite Incorporating Nitrogen-Doped Graphene Oxide, Polypyrrole, and Silica for Lithium-Ion Battery Anodes

“…38,[42][43][44][45] Conducting polymers are ideal materials for hybrid composites in lithium-ion batteries due to it is conducting backbone, high electrical conductivity, and high coulombic efficiency, making them suitable for cycling hundreds or thousands of times with minimal degradation. 46 Conducting polymers, such as polyaniline (PANI), can be employed in energy storage such as supercapacitors. [47][48][49][50] Another type of conducting polymer is PEDOT which has high flexibility and can be used as flexible supercapacitor.…”