Preparation of fluorescent nanocomposites based on gold nanoclusters self-assembly

Wang, Xiaoyu; Wang, Chun; Yang, Ning; Xia, Junhan; Li, Lidong

doi:10.1016/j.colsurfa.2018.03.059

Cited by 23 publications

(18 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Based on the host–guest interaction of cyclodextrin and adamantine, AuNCs and polymers could assemble as nanocomposites with enhanced fluorescence and stable optical properties in aqueous solutions. 30 Silver ions can induce AuNCs aggregation and Au(I)/Ag(I)–thiolate motifs formation through Ag(I)–thiolate bonds or metallophilic Ag(I)–Au(I) bonds. 31 The surface-immobilized Ag(I) adjusted the LMCT and ligand-to-metal–metal charge transfer, which resulted in enhanced emission with red-shift.…”

Section: Regulating the Optical Properties Of A Gold Nanoclustermentioning

confidence: 99%

“…In addition, we modified the cyclodextrin on AuNCs and adamantine on polymers, respectively. Based on the host–guest interaction of cyclodextrin and adamantine, AuNCs and polymers could assemble as nanocomposites with enhanced fluorescence and stable optical properties in aqueous solutions . Silver ions can induce AuNCs aggregation and Au(I)/Ag(I)–thiolate motifs formation through Ag(I)–thiolate bonds or metallophilic Ag(I)–Au(I) bonds .…”

Section: Regulating the Optical Properties Of A Gold Nanoclustermentioning

confidence: 99%

See 1 more Smart Citation

Regulating the Optical Properties of Gold Nanoclusters for Biological Applications

et al. 2020

Self Cite

View full text Add to dashboard Cite

Gold nanoclusters are promising optically functional materials because of their attractive optical properties, such as luminescence, two-photon absorption, photothermal conversion, and photodynamics. Regulating the optical functions of gold nanoclusters and improving their performance have attracted wide interest in biological applications. In this Review, we introduce the principles to manipulate both the intrinsic optical properties and the apparent optical performance of gold nanoclusters. Manipulating the surface ligands and compounding with other nanomaterials are facile and efficient strategies. Based on the regulated optical properties, the gold nanoclusters can be well applied in various biomedical applications from multimodal bioimaging toward theranostics. By correlating structures and optical properties, we expect a better utilization of the optical gold nanoclusters in the biological field.

show abstract

Section: Regulating the Optical Properties Of A Gold Nanoclustermentioning

confidence: 99%

Section: Regulating the Optical Properties Of A Gold Nanoclustermentioning

confidence: 99%

Regulating the Optical Properties of Gold Nanoclusters for Biological Applications

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…So far, there have been many reports studying on the assembly of metal NCs, in which hydrophobic forces, supramolecular interactions, or incorporation of metal ions play important roles. − , There are also literatures reporting that metal NCs can enter the metal–organic frameworks (MOFs) and chitosan/other polymers by electrostatic interaction, leading to the emission enhancement. − This work is the first example that two different metal NCs can form photoluminescent assembly without any external matrix such as MOFs and polymers.…”

Section: Resultsmentioning

confidence: 95%

Au_xAg_1–x Nanocomposites with 40-Fold Emission Enhancement Formed by the Electrostatic Assembly of Gold Nanoclusters and Silver Nanoclusters for Bioimaging and Bioanalysis

Yin

Chen

Liu

et al. 2019

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

Noble metal nanoclusters (NCs) have been widely used in bioimaging and bioanalysis due to their unique molecular-like structures and good biocompatibility. Bright nanomaterials with high quantum yields are in need for widespread applications. Unfortunately, the weak photoluminescence (PL) of metal NCs hampers their biomedical applications, and thus it is urgent to develop effective routes to enhance their brightness, especially in aqueous solutions. In this work, we reported a facile strategy to prepare highly luminescent Au x Ag1–x nanocomposites (x: molar ratio of Au) by electrostatic-induced assembly of nonluminescent glutathione (GSH) stabilized silver NCs (GSH-Ag NCs) and weak orange-emitting GSH stabilized gold NCs (GSH-Au NCs) in aqueous solutions. Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), fluorescence spectroscopy, inductively coupled plasma mass spectrometry (ICP-MS), UV–vis absorption spectroscopy, and dynamic light scattering (DLS) shed light on the mechanism of PL enhancement. It was found that the positively charged gold nanoclusters and the negatively charged silver nanoclusters formed aggregates by electrostatic force, leading to a 40-fold fluorescence intensity enhancement compared with GSH-Au NCs. This was a novel method to strengthen the fluorescence of nanoclusters with such large enhancement in aqueous solutions. With the molar ratio of Au and Ag changing from 80:1 to 2:3, the emission maximum of the Au x Ag1–x nanocomposites could be tuned from 590 to 548 nm. The electrostatic force of the Au0.50Ag0.50 nanocomposites enabled them to respond to pH. The Au0.50Ag0.50 nanocomposites were fluorescent turn-on and turn-off at pH 2.6 and pH 7.5, respectively. In this respect, they can be used as a fluorescent switch and be further used as a general recyclable pH probe in the range of 2.6–7.5. This work will inspire even better strategies to further improve the brightness of noble metal NCs.

show abstract

“…In addition, the active groups on the organic ligands enabled the AuNCs to participate in chemical reactions without affecting their optical properties . The improved stability and reactivity facilitated the fabrication of composite AuNCs with polymers for biological applications through doping and in situ reduction. − However, in most cases, AuNCs are used as independent agents, which are compounded with polymers through interfacial polymer–particle interactions. The combination of AuNCs and polymers through reactive ligands to prepare smart hydrogels has drawn considerable attention.…”

Section: Introductionmentioning

confidence: 99%

Free Radical Polymerization of Gold Nanoclusters and Hydrogels for Cell Capture and Light-Controlled Release

Zhu

Wang

Cong

et al. 2021

ACS Appl. Mater. Interfaces

Self Cite

View full text Add to dashboard Cite

Gold nanocluster (AuNC) decorated hydrogels have attracted considerable attention as versatile biomaterials. To date AuNCs and hydrogels have mainly been mixed as independent components. Here, we report the use of AuNCs as reactive monomers in the polymerization of hydrogels. We used a free radical polymerization to copolymerize AuNCs with acrylamide and N-acryloyl glycinamide to prepare stimuli-responsive smart hydrogels. Multiple CC bonds were decorated on the surface of the AuNCs as active sites for polymerization. These CC bonds not only protected the structure of the AuNCs from oxidation by free radicals during polymerization but also covalently connected the AuNCs with the polymer chains. This structure ensured good photothermal performance of the AuNCs while preserving the thermoresponsive hydrogen bonds of polymers. Moreover, the copolymerized AuNCs acted as cross-linkers, which improved the mechanical properties of the hydrogels. These smart hydrogels had good stability, efficient photothermal conversion, and a sensitive thermoresponsive. We examined their potential for capture of MDA-MB-231 cells with hyaluronic acid as target molecules. The captured cells were released under 660 nm irradiation. This process of targeted capture and light-controlled remote release could be repeatedly applied. These results suggest that systems based on AuNCs copolymerized with hydrogels have great potential for biomedical applications.

show abstract

Preparation of fluorescent nanocomposites based on gold nanoclusters self-assembly

Cited by 23 publications

References 49 publications

Regulating the Optical Properties of Gold Nanoclusters for Biological Applications

Regulating the Optical Properties of Gold Nanoclusters for Biological Applications

Au_xAg_1–x Nanocomposites with 40-Fold Emission Enhancement Formed by the Electrostatic Assembly of Gold Nanoclusters and Silver Nanoclusters for Bioimaging and Bioanalysis

Free Radical Polymerization of Gold Nanoclusters and Hydrogels for Cell Capture and Light-Controlled Release

Contact Info

Product

Resources

About

Preparation of fluorescent nanocomposites based on gold nanoclusters self-assembly

Cited by 23 publications

References 49 publications

Regulating the Optical Properties of Gold Nanoclusters for Biological Applications

Regulating the Optical Properties of Gold Nanoclusters for Biological Applications

AuxAg1–x Nanocomposites with 40-Fold Emission Enhancement Formed by the Electrostatic Assembly of Gold Nanoclusters and Silver Nanoclusters for Bioimaging and Bioanalysis

Free Radical Polymerization of Gold Nanoclusters and Hydrogels for Cell Capture and Light-Controlled Release

Contact Info

Product

Resources

About

Au_xAg_1–x Nanocomposites with 40-Fold Emission Enhancement Formed by the Electrostatic Assembly of Gold Nanoclusters and Silver Nanoclusters for Bioimaging and Bioanalysis