Preparation of Hydroxyapatite Lathlike Particles Using High‐Speed Dispersing Equipment

Abstract

Hydroxyapatite lathlike monocrystalline particles were prepared using high-energy dispersing equipment in combination with a pH shock-wave method. The Ca/P atomic ratios were very close to theoretical, and the acidic group content was very small. The particles were nonporous, with anisotropic crystal growth and average grain size ϳ140 -1300 nm in length, ϳ20 -100 nm in width, and ϳ10 -40 nm in thickness. The high-speed dispersing equipment created the proper hydrodynamic conditions for lathlike particle growth in the [001] direction. The hydroxyapatite particles formed aggregates of 1-5 m average diameter.

Effect of Hydroxide Ion Concentration on the Morphology of the Hydroxyapatite Nanorods Synthesized Using Electrophoretic Deposition

“…Different facets of the crystals have different quantity of the OH − ions and its hindrance effect. If the larger quantity of the OH − will be available at the interface, the hindrance effect of the OH − ions will be stronger on the facets which will affect [22]. To know the role of higher OH − concentration and TiO 2 , various experiments are underway.…”

Development of Cell-Responsive Nanophase Hydroxyapatite for Tissue Engineering

“…Koumoulidis et al [20] reported the synthesis of HA in the form of lath-like monocrystalline particles using the precursors of Ca(H 2 PO 4 ) 2 .H 2 O and CaCl 2 . They employed a highenergy dispersing equipment to synthesize nano HA.…”

“…The nanophase HA is therefore perceived to be beneficial in bone tissue engineering as a new generation scaffolding system. There are several methods for the synthesis of nanophase HA, which include wet chemical [14,15] , solid state [16] , hydrothermal [17,18] , mechanochemical [19] , pH shock wave [20] , and microwave processing [21] .…”

Synthesis of hydroxyapatite by using calcium carbonate and phosphoric acid in various water-ethanol solvent systems

“…Various techniques were developed for the synthesis of hydroxyapatites, based on solid state reactions [1,2], chemical precipitation reactions [3][4][5][6][7][8][9][10][11], hydrothermal reactions [12][13][14][15][16][17][18], sol-gel methods [19][20][21][22][23] and mechanochemical methods [24][25][26] using different calcium and phosphorus containing starting materials.…”