Preparation of Microemulsion from an Alkyl Polyglycoside Surfactant and Tea Tree Oil

Vo, Thuy‐Vi; Chou, Ya-Yen; Chen, Bing‐Hung

doi:10.3390/molecules26071971

Cited by 17 publications

(16 citation statements)

References 28 publications

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“…Microemulsions have found applications in various fields, such as personal care products, medicines, etc. In this work, the aqueous microemulsions of the in‐house hydrodistilled tea tree oil were prepared with Triton CG‐110 as the surfactant and propylene glycol (PPG) as the co‐surfactant, according to the phase diagrams previously established with TTO, Triton CG‐110, and PPG 23 . The TTO‐microemulsions prepared were examined for their physicochemical properties and explored for their potential applications, mainly in the DPPH antioxidant activity.…”

Section: Resultsmentioning

confidence: 99%

“…The extraction process of tea tree oil by hydrodistillation in the Clevenger system was described in detail elsewhere 23 . In this work, the Design of Experiments (DoE) strategy was applied to optimize the hydrodistillation process.…”

Section: Methodsmentioning

confidence: 99%

“…The preparation procedure of O/W microemulsions composed of tea tree oil and mixed surfactants was given in our previous report 23 . The mixed surfactant, noted as S mix , is made of Triton CG‐110 in 3 parts and propylene glycol (PPG) in 1 part by mass.…”

Section: Methodsmentioning

confidence: 99%

“…The extraction process of tea tree oil by hydrodistillation in the Clevenger system was described in detail elsewhere. 23 In this work, the Design of Experiments (DoE) strategy was applied to optimize the hydrodistillation process. The response surface methodology (RSM) with the central composite design (CCD) was employed to obtain the optimal extraction conditions.…”

Section: Optimization Of Hydrodistillation Process With the Response ...mentioning

confidence: 99%

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Surfactant‐assisted extraction of Melaleuca alternifolia (tea tree) oil by hydrodistillation and its application in microemulsion

Truong

Chen

2022

J of Chemical Tech & Biotech

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BACKGROUND: The surfactant-assisted extraction of essential oils from Melaleuca alternifolia foliage, also known as tea tree oil (TTO), was systematically studied with the design of experiments (DoE) aiming to improve the extraction of TTO. Specifically, the optimal parameters of hydrodistillation process were obtained with the response surface methodology (RSM) based on a central composite design (CCD). RESULTS:The concept of enhanced TTO extraction with the renewable nonionic Triton CG-110 surfactant was proven. An optimal extraction yield of TTO was predicted by the RSM model at 6.71 wt% under the following conditions: (i) 597 mg L −1 Triton CG-110 as liquid extractant, (ii) a ratio of liquid extractant/desiccated leaf at 25.4 mL g −1 , and (iii) 140 min for the extraction time. The presence of 650 mg L −1 Triton CG-110 in the extractant could increase the extraction rate of TTO by 17.5%, compared to that without surfactant. The forecast of the DPPH antioxidant activity of TTO by RSM was in good accordance with the measured values. Various microemulsion formulations of TTO with Triton CG-110 were developed and reported.CONCLUSION: The presence of a proper surfactant in the liquid extractant can improve the extraction of essential oils, not only in the form of yield but also in the rate of extraction. No trace of surfactant could be found in the produced essential oil because of the relatively higher boiling point and the lower volatility of the surfactant. The RSM was successfully applied to obtain the optimal extraction parameters for tea tree oil by the surfactant-enhanced hydrodistillation process.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Optimization Of Hydrodistillation Process With the Response ...mentioning

confidence: 99%

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Surfactant‐assisted extraction of Melaleuca alternifolia (tea tree) oil by hydrodistillation and its application in microemulsion

Truong

Chen

2022

J of Chemical Tech & Biotech

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“…Furthermore, the most suitable preparation scheme for an O/W microemulsion may change depending on the storage and application conditions, even for microemulsions encapsulating the same molecule. Therefore, the preparation of O/W microemulsions requires a careful experimental design to ensure the optimal conditions for their preparation [33][34][35].…”

Section: Introductionmentioning

confidence: 99%

Performance of Oleic Acid and Soybean Oil in the Preparation of Oil-in-Water Microemulsions for Encapsulating a Highly Hydrophobic Molecule

Fernández‐Peña

Mojahid

Guzmán

et al. 2021

Colloids and Interfaces

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This work analyzes the dispersion of a highly hydrophobic molecule, (9Z)-N-(1,3-dihydroxyoctadecan-2-yl)octadec-9-enamide (ceramide-like molecule), with cosmetic and pharmaceutical interest, by exploiting oil-in-water microemulsions. Two different oils, oleic acid and soybean oil, were tested as an oil phase while mixtures of laureth-5-carboxylic acid (Akypo) and 2-propanol were used for the stabilization of the dispersions. This allowed us to obtain stable aqueous-based formulations with a relatively reduced content of oily phase (around 3% w/w), that may enhance the bioavailability of this molecule by its solubilization in nanometric oil droplets (with a size range of 30–80 nm), that allow the incorporation of a ceramide-like molecule of up to 3% w/w, to remain stable for more than a year. The nanometric size of the droplet containing the active ingredient and the stability of the formulations provide the basis for evaluating the efficiency of microemulsions in preparing formulations to enhance the distribution and availability of ceramide-like molecules, helping to reach targets in cosmetic and pharmaceutical formulations.

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Nanoemulsion as an Effective Inhibitor of Biofilm-forming Bacterial Associated Drug Resistance: An Insight into COVID Based Nosocomial Infections

Raj

Dhamodharan

Thanigaivel

et al. 2022

Biotechnol Bioproc E

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Antibiotic overuse has resulted in the microevolution of drug-tolerant bacteria. Understandably it has become one of the most significant obstacles of the current century for scientists and researchers to overcome. Bacteria have a tendency to form biofilm as a survival mechanism. Biofilm producing microorganism become far more resistant to antimicrobial agents and their tolerance to drugs also increases. Prevention of biofilm development and curbing the virulency factors of these multi drug resistant or tolerant bacterial pathogens is a newly recognised tactic for overcoming the challenges associated with such bacterial infections and has become a niche to be addressed. In order to inhibit virulence and biofilm from planktonic bacteria such as, Pseudomonas aeruginosa , Acinetobacter baumannii , and others, stable nanoemulsions (NEs) of essential oils (EOs) and their bioactive compounds prove to be an interesting solution. These NEs demonstrated significantly greater anti-biofilm and anti-virulence activity than commercial antibiotics. The EO reduces disease-causing gene expression, which is required for pathogenicity, biofilm formation and attachment to the surfaces. Essential NE and NE-loaded hydrogel surface coatings demonstrates superior antibiofilm activity which can be employed in healthcare-related equipments like glass, plastic, and metal chairs, hospital beds, ventilators, catheters, and tools used in intensive care units. Thus, anti-virulence and anti-biofilm forming strategies based on NEs-loaded hydrogel may be used as coatings to combat biofilm-mediated infection on solid surfaces.

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Preparation of Microemulsion from an Alkyl Polyglycoside Surfactant and Tea Tree Oil

Cited by 17 publications

References 28 publications

Surfactant‐assisted extraction of Melaleuca alternifolia (tea tree) oil by hydrodistillation and its application in microemulsion

Surfactant‐assisted extraction of Melaleuca alternifolia (tea tree) oil by hydrodistillation and its application in microemulsion

Performance of Oleic Acid and Soybean Oil in the Preparation of Oil-in-Water Microemulsions for Encapsulating a Highly Hydrophobic Molecule

Nanoemulsion as an Effective Inhibitor of Biofilm-forming Bacterial Associated Drug Resistance: An Insight into COVID Based Nosocomial Infections

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