Preparation of Nanocapsules with Alginate/Polylysine Complex Wall

Abe, Masahiko; Tanaka, Kensuke; Nakayama, Ai; Kondo, Tamotsu; Tsuchiya, Koji; Tantayakom, Veerapat; Ohkubo, Takahiro; Sakai, Hideki

doi:10.5650/jos.55.615

Cited by 4 publications

(4 citation statements)

References 9 publications

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“…W/O emulsions were prepared with the laboratory-made apparatus for electrocapillary emulsification [7,8]. Briefly, the apparatus consists of the emulsification part, the applied electric potential and liquid dropping rate controlling part, a CCD camera and a monitor.…”

Section: Preparation Of Polyurea Capsulesmentioning

confidence: 99%

Preparation of polyurea capsules using electrocapillary emulsification

Sakai

Tanaka

Fukushima

et al. 2008

Colloids and Surfaces B: Biointerfaces

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Section: Preparation Of Polyurea Capsulesmentioning

confidence: 99%

Preparation of polyurea capsules using electrocapillary emulsification

Sakai

Tanaka

Fukushima

et al. 2008

Colloids and Surfaces B: Biointerfaces

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“…The electrostatic atomization is a technique for the atomization of liquid with an electrohydrodynamic (EHD) force, and many studies are reported in recent years . The electrostatic atomization could be classified into three systems as follows: (1) a liquid dispersion into a gas (L/G) system, (2) gas dispersion into a liquid (G/L) system, and (3) a liquid dispersion into a liquid (L/L) system.…”

Section: Introductionmentioning

confidence: 99%

“…As mentioned earlier, although electrostatic emulsification has potential ability to prepare a uniform nano‐size droplet, reports on the production of drug carrier are few. Some attempts for the drug carrier production were conducted by Abe et al , such as the nano‐capsule of alginate/polylysine complex, which has sizes ranging from 100–500 nm, the Poly(2‐ethylcyanoacrylate), which has sizes ranging from 100–300 nm, and the poly‐urea capsule of around 200 nm …”

Section: Introductionmentioning

confidence: 99%

Chitosan nano‐spheres production by electrostatic emulsification technique

Takahashi

Itobayashi

Shono

et al. 2011

Asia-Pacific J Chem Eng

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Electrostatic emulsification of an acidic chitosan solution into an organic solvent was examined for chitosan sphere production of controlled size ranging from nano to submicron scale. Droplets formation by the electrostatic emulsification was observed with a charge-coupled device camera. The diameters of generated water in oil emulsion droplets were measured by dynamic light scattering. At voltages greater than critical voltage, over which the electrostatic emulsification occurs, the droplet diameter "D" depended on the applied voltage "U", the electrode distance "L", and the flow rate of aqueous phase "F". An empirical formula for the relationship between the "D" and "U", "L" and "F" was obtained as D/U À0.65 L 0.43 F 0.14 . Further, the chitosan spheres were obtained by cross-linking the emulsion droplets with glutaraldehyde, and were observed by using a scanning electron microscope. The chitosan nano-spheres of the size equal to the emulsion droplet were successfully obtained by the cross-linking of the chitosan and controlling a specific gravity difference of dispersed phase and continuous phase. These results show that the electrostatic emulsification is an excellent technique for the preparation of functional particles of controlled size ranging from nano to submicron scale.

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“…Much smaller gel particles are expected to be obtained if they are prepared at the water/oil interface via emulsion droplet. We have recently reported a new preparation method of calcium alginate gel particles in which an aqueous polyelectrolyte solution was dispersed in an oil phase containing oil-soluble gelling agent obtained by modifying a surfactant with calcium ion and gelation occurred on the surface of each aqueous droplet 9 .…”

mentioning

confidence: 99%

Preparation of Carrageenan-Polyethyleneimine Nanocapsules Using Electrocapillary Emulsification Technique

Sakai¹,

Fukushima²,

Satoh³

et al. 2009

Journal of the Japan Society of Colour Material

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The present paper proposes a novel preparation method of carrageenan-polyethyleneimine complex capsules in the submicron size range using the interfacial gelling reaction at W/O type emulsion. A W/O emulsion was prepared by adding dropwise aqueous τ-carrageenan solution into cyclohexane containing sorbitan monooleate through a microsyringe. Carrageenan gel particles were then prepared by adding the emulsion into a cyclohexane solution containing Ca AOT calcium bis 2-ethylhexyl sulfosuccinate to cause gelation of aqueous droplets. The gel particles thus prepared were coated with polyethyleneimine to improve their stability in water. Capsules with sizes ranging from 100 to 300 nm were obtained when an apparatus for electrocapillary emulsification was used in the preparation step of W/O emulsion. The use of calcium salt of dimyristoyl phosphatidyl glycerol, a constituent of biomembrane, as gelling agent gave capsules of sizes in the submicron range.

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Preparation of Nanocapsules with Alginate/Polylysine Complex Wall

Cited by 4 publications

References 9 publications

Preparation of polyurea capsules using electrocapillary emulsification

Preparation of polyurea capsules using electrocapillary emulsification

Chitosan nano‐spheres production by electrostatic emulsification technique

Preparation of Carrageenan-Polyethyleneimine Nanocapsules Using Electrocapillary Emulsification Technique

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