Preparation of nanocellulose and its applications in wound dressing: A review

Yang, Chen; Zhu, Yaqin; Tian, Zhiwei; Zhang, Chunmei; Han, Xiaoshuai; Jiang, Shaohua; Liu, Kunming; Duan, Gaigai

doi:10.1016/j.ijbiomac.2023.127997

Cited by 24 publications

(3 citation statements)

References 180 publications

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“…Menurut Serhan et al, (2020) bahan kontrol yang digunakan di laboratorium kimia klinis yaitu serum kontrol komersial merupakan bahan kontrol yang dapat dibeli secara langsung dalam bentuk jadi. Akan tetapi, bahan kontrol komersial memiliki kekurangan yaitu harganya yang mahal, sehingga menyebabkan terbatasnya persediaan bahan kontrol akibat harganya yang sulit dijangkau (Yang et al, 2024). Oleh karena itu perlu digunakan bahan pengendali alternatif yaitu bahan pengendali buatan sendiri berupa pooled serum.…”

Section: Pendahuluanunclassified

Edukasi Pemanfaatan Pooled Sera Sebagai Bahan Kontrol Alternatif Untuk Pemantapan Mutu Internal Di Laboratorium

Bastian,

Ulva

2024

JAI

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Quality control adalah serangkaian pengendalian yang dilakukan untuk mengevaluasi proses pengujian. Meningkatnya otomatisasi di bidang klinis laboratorium telah meningkatkan kebutuhan material QC untuk memantau kinerja laboratorium. Salah satunya adalah di laboratorium kimia klinis, dimana peralatan harus dikalibrasi menggunakan bahan referensi yang tersedia secara komersial sebelum pengujian dapat dilakukan. Serum kontrol yang tersedia secara komersial dapat dibeli dengan harga tinggi. Oleh karena itu, diperlukan bahan pengendalian alternatif buatan sendiri, yaitu Pooled Sera. Tujuan kegiatan untuk memberikan pengetahuan mengenai pentingnya Pemanfaatan Pooled Sera Sebagai Bahan Kontrol Alternatif Untuk Pemantapan Mutu Internal di Laboratorium. Metode kegiatan yang digunakan yaitu sosialisasi dan edukasi melalui media poster dengan tujuan dapat meningkatkan pengetahuan dan pemahaman pada petugas mengenai pentingnya Pemanfaatan Pooled Sera Sebagai Bahan Kontrol Alternatif Untuk Pemantapan Mutu Internal di Laboratorium. Terdapat pemahaman dan peningkatan hasil edukasi pada petugas laboratorium dengan nilai pretest 45,75 dan postest 85,83. Petugas Laboratorium RSUD Kayuagung telah memahami tentang pemanfaatan pooled sera sebagai bahan kontrol alternatif untuk pemantapan mutu internal di laboratorium.

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Section: Pendahuluanunclassified

Edukasi Pemanfaatan Pooled Sera Sebagai Bahan Kontrol Alternatif Untuk Pemantapan Mutu Internal Di Laboratorium

Bastian,

Ulva

2024

JAI

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“…Additionally, MCC possesses the ability to combine filling, thickening, and emulsifying functions, and demonstrates effective emulsification of oily substances. Due to its attributes of extensive biodegradability, robust stiffness, and elevated crystallinity, MCC has the potential to serve as a reinforcing agent for enhancing the mechanical properties and thermal stability of polymers. , The user has provided a numerical reference without any accompanying text or context. The effectiveness of MCC in enhancing the capabilities of the PLA was also observed.…”

Section: Introductionmentioning

confidence: 99%

Biocomposites of Poly(Lactic Acid) and Microcrystalline Cellulose: Influence of the Coupling Agent on Thermomechanical and Absorption Characteristics

Gorgun,

Ali,

Islam

2024

ACS Omega

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In this study, poly(lactic acid) (PLA) and microcrystalline cellulose (MCC)-based green biocomposites were developed using a solution casting technique. Essentially, the bonding between PLA and MCC is quite feeble; therefore, the current study is conducted to strengthen the bonding by incorporating a coupling agent, thereby enhancing the overall quality of the biocomposites. Thus, the present study aimed to examine the influence of combined coupling agents�maleic anhydride (MAH) and maleic acid (MA) (MAH−MA)�on the properties of polylactic acid (PLA)/microcrystalline cellulose (MCC) biocomposites. The investigation also encompassed an examination of the impact of MCC loading (2, 3, and 5% w/w) into a PLA matrix. The Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) examination revealed the interfacial interaction and adhesion among MCC, PLA, and coupling agents and the formation of biocomposites. The incorporation of MAH−MA led to improved mechanical properties of the PLA/MCC biocomposites. Furthermore, the incorporation of MAH−MA into the PLA/3 wt % MCC composite exhibited enhancements in both the tensile strength and tensile modulus, accompanied by a reduced elongation at break. In addition, it is worth noting that the thermogravimetric analysis (TGA) curve of the PLA composite with 3% w/w of MCC and MAH−MA displayed a significant decrease in weight beyond a temperature threshold of 492.65 °C. The water absorption demonstrates that the incorporation of MAH−MA into the PLA/MCC composite led to advantageous water barrier characteristics. The observed improvements were attributed to the efficient dispersion of MCC at the most favorable amount of coupling agents, along with the chemical interactions involving grafting and esterification between MCC and the MAH−MA coupling agent. Furthermore, the incorporation of MAH−MA into the PLA/3% (w/w) MCC composite exhibited enhancements in both the tensile strength and tensile modulus, accompanied by a reduction in the elongation percentage at break. The experimental results about water absorption demonstrate that the incorporation of MAH−MA into the PLA/MCC composite led to advantageous water barrier characteristics. These improvements were attributed to good MCC dispersion and the chemical interactions involving grafting and esterification between the MCC and the MAH−MA coupling agent.

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“…2 Hence, maintaining and improving the wound microenvironment is regarded as an effective way to reduce infection and promote healing. 3 Current wound care methods mainly include local debridement, 4 the use of dressings, 5 the use of antibiotics, 6 and the use of growth factors. 7 However, these existing measures can lead to problems such as secondary damage, drug resistance, and low bioavailability.…”

Section: Introductionmentioning

confidence: 99%

Photopolymerizable and Antibacterial Hydrogels Loaded with Metabolites from Lacticaseibacillus rhamnosus GG for Infected Wound Healing

Han,

Yin,

Wang

et al. 2024

Biomacromolecules

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In response to increasing antibiotic resistance and the pressing demand for safer infected wound care, probiotics have emerged as promising bioactive agents. To address the challenges associated with the safe and efficient application of probiotics, this study successfully loaded metabolites from Lacticaseibacillus rhamnosus GG (LGG) into a gelatin cross-linked macromolecular network by an in situ blending and photopolymerization method. The obtained LM-GelMA possesses injectability and autonomous healing capabilities. Importantly, the incorporation of LGG metabolites endows LM-GelMA with excellent antibacterial properties against Staphylococcus aureus and Escherichia coli, while maintaining good biocompatibility. In vivo assessments revealed that LM-GelMA can accelerate wound healing by mitigating infections induced by pathogenic bacteria. This is accompanied by a reduction in the expression of key proinflammatory cytokines such as TNF-α, IL-6, VEGFR2, and TGF-β, leading to increased re-epithelialization and collagen formation. Moreover, microbiological analysis confirmed that LM-GelMA can modulate the abundance of beneficial wound microbiota at family and genus levels. This study provides a facile strategy and insights into the functional design of hydrogels from the perspective of wound microenvironment regulation.

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Preparation of nanocellulose and its applications in wound dressing: A review

Cited by 24 publications

References 180 publications

Edukasi Pemanfaatan Pooled Sera Sebagai Bahan Kontrol Alternatif Untuk Pemantapan Mutu Internal Di Laboratorium

Edukasi Pemanfaatan Pooled Sera Sebagai Bahan Kontrol Alternatif Untuk Pemantapan Mutu Internal Di Laboratorium

Biocomposites of Poly(Lactic Acid) and Microcrystalline Cellulose: Influence of the Coupling Agent on Thermomechanical and Absorption Characteristics

Photopolymerizable and Antibacterial Hydrogels Loaded with Metabolites from Lacticaseibacillus rhamnosus GG for Infected Wound Healing

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