“…Due to the abundant active sites on their surface, their physicochemical and photoluminescence properties are easy to be adjusted; CQDs have been widely used in fields such as photovoltaic energy devices, 1,2 information encryption, anticounterfeiting, 3,4 and sensor detection, 5 and especially have great potential for application in the bio-imaging and medical fields. 6–8 Generally, the formation pathway of CQDs from small organic molecules, such as citric acid, o -phenylenediamine and m -phenylenediamine, mainly involves dehydration, polymerization, aromatization, and condensation. 9 These small organic molecules are structurally simple and can easily undergo the above reactions.…”