Preparation of Photo-responsive DNA Supramolecular Hydrogels and Their Application as UV Radiometers

Ding, Yuqiao; Li, Yujie; Bo, Yang; Pan, Yufan; Cheng, Jia-feng; Meng, Siwen; Li, Dongsheng; Xu, Lijin; Dong, Yuanchen

doi:10.1007/s40242-023-2329-5

Cited by 4 publications

(2 citation statements)

References 33 publications

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“…Such materials are called “responsive” or “switchable” materials. These external stimuli include light, temperature, , pH, , magnetic field, , etc. These materials have high application value and broad application prospects, , such as controllable drug delivery, − intelligent sensors, catalytic control, and so on.…”

Section: Introductionmentioning

confidence: 99%

Preparation of CO₂-Responsive Biobased Ternary Composite Microgel and Its Application in Reservoir Gas Channeling Plugging

Gu,

Tu,

Zhou

2024

Energy Fuels

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In this paper, a biobased ternary composite microgel (CS-DP-AA) was designed and prepared, which was based on chitosan and had a reversible response to CO 2 . The synthesis of CS-DP-AA microgel was proved by infrared spectroscopy, chromatography−mass spectrometry, X-ray photoelectron spectroscopy, and Raman spectroscopy. The structure and properties of CS-DP-AA microgel before and after CO 2 response were characterized by scanning electron microscope, transmission electron microscope, ultraviolet visible spectrophotometer, laser particle size analyzer, zeta potentiometer, and other instruments, and the CO 2 response mechanism was explored. The results show that CS-DP-AA microgel had great CO 2 response performance and stability, and the UV transmittance could still reach 90.01% (relative) at 268.98 h after CO 2 response. Subsequently, the rheological properties of CS-DP-AA microgel were evaluated by a rotary rheometer, which shows that CS-DP-AA microgel after the CO 2 response had obvious viscoelasticity. Although shear thinning appeared with the increase in shear rate, the CS-DP-AA microgel after the CO 2 response still had good viscosity under high temperature, high pressure, and high shear rate, which proves that it had great rheological properties. On the other hand, the ability of CS-DP-AA microgel to plug gas channeling in reservoirs was evaluated by a dual-core parallel-core physical simulation experimental device. The results show that the CS-DP-AA microgel injected into the core can indeed react with the CO 2 adsorbed in the pores of the porous core and plug the larger pores. After the response, the resistance coefficient of the system increased significantly, reaching 80 times that of the previous value. It has been shown that CS-DP-AA microgel can indeed block gas channeling in oil reservoirs, expand the sweep efficiency and swept volume of the CO 2 gas drive, contribute to the recovery rate of oil reservoirs, and ensure the smooth development of oil reservoirs, which has a good application prospect in plugging gas channeling in oil reservoirs.

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Section: Introductionmentioning

confidence: 99%

Preparation of CO₂-Responsive Biobased Ternary Composite Microgel and Its Application in Reservoir Gas Channeling Plugging

Gu,

Tu,

Zhou

2024

Energy Fuels

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“…In comparison to other hydrogels, a DNA supramolecular hydrogel is dynamic, mechanically strong, biocompatible, and has excellent molecular permeability. − To tune the gelation dynamic process, researchers have developed various methods for the preparation of a DNA hydrogel, such as the clamped hybridization chain reaction (C-HCR, Figure S1), which performs good controllability and could benefit the incorporation into the liposomes. Furthermore, it has also been proven that a DNA hydrogel performed an extraordinary antishear protective effect both in vitro and in vivo due to its tunable mechanical property and injectability. − Thus, these extraordinary properties have allowed DNA hydrogels to be a promising candidate for use as a flexible internal support to improve the structural stability of LNPs …”

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Increase Nebulization Stability of Lipid Nanoparticles by Integrating a DNA Supramolecular Hydrogel

Wei

Cheng

et al. 2023

ACS Macro Lett.

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Nebulized lipid nanoparticles (LNPs) have been considered as potential therapies for genetic disease as well as infectious disease. However, the sensitivity of LNPs to high shear stress during the nebulization process results in loss of the integrity of the nanostructure and the capability of delivering active pharmaceutical ingredients. Herein we have provided a fast extrusion method to prepare liposomes incorporated with a DNA hydrogel (hydrogel-LNPs) to improve the stability of the LNPs. Taking advantage of the good cellular uptake efficiency, we also demonstrated the potential of hydrogel-LNPs in delivering small molecular doxorubicin (Dox) and nucleic acid drugs. This work provides not only highly biocompatible hydrogel-LNPs for aerosol delivery, but also a strategy to regulate the elasticity of LNPs, which will benefit the potential optimization of drug delivery carriers.

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DNA-based supramolecular hydrogels: From construction strategies to biomedical applications

Chen

et al. 2023

Chinese Chemical Letters

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Preparation of Photo-responsive DNA Supramolecular Hydrogels and Their Application as UV Radiometers

Cited by 4 publications

References 33 publications

Preparation of CO₂-Responsive Biobased Ternary Composite Microgel and Its Application in Reservoir Gas Channeling Plugging

Preparation of CO₂-Responsive Biobased Ternary Composite Microgel and Its Application in Reservoir Gas Channeling Plugging

Increase Nebulization Stability of Lipid Nanoparticles by Integrating a DNA Supramolecular Hydrogel

DNA-based supramolecular hydrogels: From construction strategies to biomedical applications

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Preparation of Photo-responsive DNA Supramolecular Hydrogels and Their Application as UV Radiometers

Cited by 4 publications

References 33 publications

Preparation of CO2-Responsive Biobased Ternary Composite Microgel and Its Application in Reservoir Gas Channeling Plugging

Preparation of CO2-Responsive Biobased Ternary Composite Microgel and Its Application in Reservoir Gas Channeling Plugging

Increase Nebulization Stability of Lipid Nanoparticles by Integrating a DNA Supramolecular Hydrogel

DNA-based supramolecular hydrogels: From construction strategies to biomedical applications

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Preparation of CO₂-Responsive Biobased Ternary Composite Microgel and Its Application in Reservoir Gas Channeling Plugging

Preparation of CO₂-Responsive Biobased Ternary Composite Microgel and Its Application in Reservoir Gas Channeling Plugging