Preparation of Poly(butyl cyanoacrylate) Nanoparticles by Aqueous Dispersion Polymerisation in the Presence of Insulin

Soap-free emulsion polymerization of styrene using poly(methacrylic acid) macro-RAFT agent

“…The conversion was 38% in 12 h. The low molecular weight distribution of PMAA confirms that the RAFT method successfully worked for the preparation of macro-RAFT agent. 1 H NMR spectroscopy is used to verify the chemical structure of the synthesized PMAA macro-RAFT agent, polystyrene (PS), and PS synthesized using the PMAA macro-RAFT agent [P(S-b-MAA)]. Fig.…”

“…Nano-sized polymeric particles with monodisperse size distribution have been utilized in various applications such as ion adsorbents [1], fillers in polymers, pigments, instrument calibration standards [2], diagnostics and drug carriers [3], reaction catalysis [4], environmental protection [5], etc. Water-borne polymerizations such as emulsion and suspension polymerizations are of great importance in industrial application as they provide environmental friendly processes, remove the reaction heat easily during polymerization, and assure the feasible handling of the final product having a low viscosity [6][7][8].…”

Synthesis and characterization of polyacrylonitrile nanoparticles by dispersion/emulsion polymerization process

“…Nanometer-sized polymeric particles of narrow size distribution have attracted much attention in many applications such as ion adsorbents [1,2], fillers in polymers [3,4], pigments [5,6], calibration standards [7], diagnostics [8], drug carriers [9][10][11][12], reaction catalysis [13], environmental protection [14], etc. Due to their simplicity and the wide range of monomers that can be successfully polymerized, the common mechanisms for preparing these particles are dispersion and emulsion polymerization.…”

Poly(alkycyanoacrylate) nanoparticles for enhanced delivery of therapeutics – is there real potential?

“…in vitro Antithrombotic activity preserved [76] PS80-PBCA In addition, the high reactivity of the monomers and competitive polymerisation initiation by any kind of nucleophile leading to possible co-polymerisation adds to the complexity of these studies and their interpretation. Under these circumstances polymerisation may become uncontrollable and often results in polymer aggregates rather than nanoparticles [16,58,59]. Addition of the drug to the polymerisation medium after its initiation or to preformed polymers has been suggested as an alternative to avoid interference of the drug with the polymerisation [22].…”