Preparation of PVA/Polymer Colloid nanocomposite Hydrogel Using PS-PNVA Particles

Toyoda, Naoya; Yamamoto, Tetsuya; Arakawa, Kenji; Teshima, Aiko

doi:10.1246/cl.181042

Cited by 6 publications

(3 citation statements)

References 28 publications

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“…As earlier mentioned PVA is commonly referred to as a water-soluble excipient, but PVA forms a physical hydrogel in an aqueous medium [ 50 ]. Of course, concentration conditions must be taken into account.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Biodegradable PVA-Based 3D Printed Carriers during Dissolution

et al. 2021

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The presence of additive manufacturing, especially 3D printing, has the potential to revolutionize pharmaceutical manufacturing owing to the distinctive capabilities of personalized pharmaceutical manufacturing. This study’s aim was to examine the behavior of commonly used polyvinyl alcohol (PVA) under in vitro dissolution conditions. Polylactic acid (PLA) was also used as a comparator. The carriers were designed and fabricated using computer-aided design (CAD). After printing the containers, the behavior of PVA under in vitro simulated biorelevant conditions was monitored by gravimetry and dynamic light scattering (DLS) methods. The results show that in all the dissolution media PVA carriers were dissolved; the particle size was under 300 nm. However, the dissolution rate was different in various dissolution media. In addition to studying the PVA, as drug delivery carriers, the kinetics of drug release were investigated. These dissolution test results accompanied with UV spectrophotometry tracking indirectly determine the possibilities for modifying the output of quality by computer design.

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Section: Resultsmentioning

confidence: 99%

Evaluation of Biodegradable PVA-Based 3D Printed Carriers during Dissolution

et al. 2021

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“…Polymer core particles were synthesized without removing the PNVA layers during the preparation of the silica shell using the Stöber method . PNVA adsorbed on the polystyrene particles acted as a catalyst for the synthesis of silica and as a stabilizer for maintaining the dispersion stability of the polymer colloid. ,− Tetraethyl orthosilicate (TEOS, Nacalai Tesque, Inc.) was used as the precursor for the synthesis of the silica shell, and 1-propanol (Nacalai Tesque, Inc.) was used as the solvent for TEOS. In this study, VA-044, which is a water-soluble initiator and dissolves in the aqueous phase, was used due to its low 10 h half-life temperature (44 °C).…”

Section: Methodsmentioning

confidence: 99%

Decomposing Oil-Soluble Initiators in Particles: A Template-Free Method for the Preparation of Hollow Polymer and Silica Particles

Yamamoto

Tsutsumi

2021

ACS Omega

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Nanovoids contained in hollow particles render them potential drug carriers. However, conventional methods for the synthesis of these particlhes involve complex processes. In this study, we developed a template-free method for the synthesis of hollow polymer and silica particles by initially preparing polystyrene core particles containing 2,2′-azobis(2-methylbutyronitrile) (V-59) through soap-free emulsion polymerization. The subsequent generation of nitrogen gas inside these particles upon the decomposition of V-59 at 70 °C led to the formation of voids. In addition, silica shells were synthesized on the surfaces of the V-59-containing polystyrene core particles through a sol–gel reaction at 40 °C, following which voids were formed by the decomposition of V-59 at 70 °C. The developed method involves straightforward steps and is environmentally friendly, as it does not require the use of surfactants, organic solvents, or templates.

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“…Poly (vinyl alcohol) (PVA) is a low-cost biodegradable polymer that has properties such as hydrophilicity and good film forming ability, which makes it suitable for membrane formation (AHMAD et al, 2012;BABU et al, 2017;TOYODA et al, 2019). The use of this polymer is not reported as a direct waterproofing system in sanitary landfills, but it has been widely used in desalination and ultrafiltration membranes (RHIN et al, 2004;SONKER et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Kinetic of Cu2+ Adsorption in the PVA Membranes Crosslinked with Sulfosuccinic and Citric Acids

et al. 2021

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Membrane of Poly (vinyl alcohol) (PVA) crosslinked with sulfosuccinic acid (SSA) and citric acid (CA) were characterized for the adsorption of copper ions (Cu2+). Usually the membranes used for this application have inorganic materials in their structure. However, when using only these acids, it was verified that the membrane containing SSA presents less swelling than the PVA and absorbs a higher content of Cu2+ when compared to the membrane containing CA. Therefore, it can be assumed that the membrane containing SSA can be used to cover soils that need protection against this type of ion. leaching. Kinetic models of diffusional and chemical control were used to understand the interaction phenomena of adsorption of ions and membranes. The mixed control kinetic model was also evaluated, in which it was possible to evaluate different parameters regarding the interaction ions and membranes. The obtained results indicated that the developed process has relevant utility. The kinetic modeling results contribute to a better understanding of heating phenomena of adsorption and also to the development of new cleaner technologies.

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Preparation of PVA/Polymer Colloid nanocomposite Hydrogel Using PS-PNVA Particles

Cited by 6 publications

References 28 publications

Evaluation of Biodegradable PVA-Based 3D Printed Carriers during Dissolution

Evaluation of Biodegradable PVA-Based 3D Printed Carriers during Dissolution

Decomposing Oil-Soluble Initiators in Particles: A Template-Free Method for the Preparation of Hollow Polymer and Silica Particles

Evaluation of the Kinetic of Cu2+ Adsorption in the PVA Membranes Crosslinked with Sulfosuccinic and Citric Acids

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