Preparation of Pyridine-2(1h)-Thiones From Chalcones

Synthesis of heterocyclic compounds by the reactions of exocyclic α,β‐unsaturated ketones

“…Cyanoacetic acid derivatives are convenient and versatile reagents for the synthesis of a wide variety of heterocyclic ring systems by their reactions with α,β-e n o n e s [ 119,120]. Numerous pyridine type compounds were obtained starting from chalcones and related α,β-unsaturated ketones by their base-catalyzed reactions with these reagents.…”

Applications of Lawesson′s Reagent in Organic and Organometallic Syntheses

“…The preparation of pyridine-2(1H)-thiones was described by Soto et al 141 Scheme 39 Preparation of a thioimide 99 142…”