Preparation of substituted carbonyl compounds by catalytic dehydrogenation of substituted alcohols

Abstract

Abstract:Possibilities for the preparation of substituted ketones by catalytic dehydrogenation of corresponding secondary alcohols were explored using a ZnO-Cr,O, catalyst at 370-4OOC. It was found that addition of about 1 w t x of sodium to the catalyst increases the yield of the ketone because the competitive dehydration of the alcohol is suppressed. Further improvement of the process was achieved by adding 20 wtx, of water to the alcohol feed, which inhibited catalyst deactivation. Preparative experiments were conducted and 1 -methoxy-2-propanone, 1 -methoxy-2-butanone, 1 -phenoxy-2-propanone and 2-methoxy-1 -cyclohexanone were obtained.

Catalytic Oppenauer oxidation of secondary alcohols over post-synthesized Sn-Beta

“…In this contribution, a set of Sn-Beta catalysts were successfully prepared by a simple post-synthesis method, in which dealumination of the parent zeolite and Sn incorporation via a solid-state ion-exchange method are involved. In view of the value-added methoxyacetone (MOA) in the grass herbicide industry and biomass valorization 12,13 and the great challenge in the synthesis of MOA, [14][15][16][17][18] the Oppenauer oxidation of 1-methoxy-2-propanol (MOP) to MOA, as well as an extended substrate scope of secondary alcohols, was studied over Sn-Beta catalysts for the first time. With the aid of a combination of advanced spectroscopic characterization and structure-performance correlation, we can identify that open framework Sn species are the intrinsic active sites with a superior turnover rate (TOR) in Oppenauer oxidation compared with other counterparts, for example, closed framework Sn and extraframework Sn species.…”