Preparation of surface-functionalized electrospun PVA nanowebs for potential remedy for SARS-CoV-2

Ayodeji, Olukayode James; Khyum, Mirza M.O.; Afolabi, Racheal T.; Smith, Ernest; Kendall, Ron; Ramkumar, Seshadri

doi:10.1016/j.hazadv.2022.100128

Cited by 8 publications

(6 citation statements)

References 32 publications

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“…4(b) , PVA(Eo) and PVA(Eo)@EC(Eo) both exhibit the absorption peaks of PVA. 38 The broad absorption peak at 3285 cm −1 was assigned to the O–H stretching vibration in PVA, the absorption peak at 2922 cm −1 was ascribed to the C–H stretching vibration, and the absorption peak at 1092 cm −1 was attributed to the C–O stretching vibration of the alcoholic hydroxyl group in PVA; 36 these are the characteristic absorption peaks of pure PVA. PVA(Eo)@EC(Eo) shows a stronger C–O stretching vibration peak of the alcohol hydroxyl group at 1092 cm −1 than the pure PVA film, which is attributed to the greater number of C–O groups in EC(Eo).…”

Section: Resultsmentioning

confidence: 99%

Superhydrophobic and highly moisture-resistant PVA@EC composite membrane for air purification

et al. 2022

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Section: Resultsmentioning

confidence: 99%

Superhydrophobic and highly moisture-resistant PVA@EC composite membrane for air purification

et al. 2022

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“…The recent outbreak of COVID-19 has dramatically highlighted the need for personal protection devices against bioaerosols and airborne pathogens. Several works have been dedicated to the fabrication of electrospun nanofiber filters and the relative assessment of antibacterial properties [49,50,58,60,64,70], or they plan to assess them in future studies [62]. All the antimicrobial activity tests have been performed using the zone of inhibition test, basically following ISO 20645:2004 or the protocols adapted from this standard ISO for the determination of the effect of antibacterial treatments applied to woven, knitted, and other flat textiles [63].…”

Section: Focused Discussion On Critical Issuesmentioning

confidence: 99%

“…Ayodeji et al (2022) have recently explored the development of a PVA/ZnO electrospun nanoweb functional surface to be used as a component of a multilayer barrier of functional face masks. Future studies will be required to characterize the PVA/ZnO nanowebs, with the assessment of the antiviral and/or antibacterial properties [62]. Sol-gel electrospinning processing has been proposed by des Ligneris et al (2019) for the engineering of composite nanofiber membranes of PVA crosslinked with copper (II) acetate.…”

Section: Electrospun Water-soluble Synthetic Polymers For Multifuncti...mentioning

confidence: 99%

Application of Electrospun Water-Soluble Synthetic Polymers for Multifunctional Air Filters and Face Masks

et al. 2022

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The worsening of air quality is an urgent human health issue of modern society. The outbreak of COVID-19 has made the improvement of air quality even more imperative, both for the general achievement of major health gains and to reduce the critical factors in the transmission of airborne diseases. Thus, the development of solutions for the filtration of airborne pollutants is pivotal. Electrospinning has gained wide attention as an effective fabrication technique for preparing ultrafine fibers which are specifically tailored for air filtration. Nevertheless, the utilization of harmful organic solvents is the major barrier for the large-scale applicability of electrospinning. The use of water-soluble synthetic polymers has attracted increasing attention as a ‘green’ solution in electrospinning. We reported an overview of the last five years of the scientific literature on the use of water-soluble synthetic polymers for the fabrication of multifunctional air filters layers. Most of recent studies have focused on polyvinyl alcohol (PVA). Various modifications of electrospun polymers have been also described. The use of water-soluble synthetic polymers can contribute to the scalability of electrospinning and pave the way to innovative applications. Further studies will be required to fully harness the potentiality of these ‘greener’ electrospinning processes.

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“…These functionalized materials exhibit the results of inflammatory process and biocompatibility. However, we also found that several types of materials are used in electrospinning to produce electrospun nanofibers, i.e., poly(vinyl alcohol) [38], poly(ethylene glycol) [39], polyamide [40], poly(vinylidene fluoride) [41], polycaprolactone [42], and chitosan [43].…”

Section: Introductionmentioning

confidence: 90%

Innovative Electrospun Nanofiber Mats Based on Polylactic Acid Composited with Silver Nanoparticles for Medical Applications

Jamnongkan,

Sirichaicharoenkol,

Kongsomboon

et al. 2024

Polymers

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Nanofibers are some of the most attractive materials that can modify functionalities for developing new kinds of specific applications and are mainly used as a biomedical material. Herein, we designed and prepared antibacterial nonwoven fiber mats of PLA and PLA composited with Ag nanoparticles by electrospinning. The effects of varying filler contents on their chemical, surface morphology, thermal, water absorbency, and antibacterial properties were investigated using FTIR, SEM/EDS, DSC, swelling ratio, and qualitative and quantitative antibacterial tests. FTIR and EDS spectra indicated that Ag nanoparticles were incorporated in the PLA without chemical bonding. SEM revealed that the average diameter of the PLA nanofibers containing the Ag nanoparticles was more significant than those without those particles. In addition, fiber diameters are proportional to the amount of Ag nanoparticle contents. DSC indicated that the Ag nanoparticles can be incorporated within the PLA matrix without strongly affecting their thermal properties. Moreover, the crystallinity of the composite nonwoven fiber mats was higher than those of fiber mats in the neat PLA. However, TGA revealed that the loaded Ag can improve the thermal stability of the PLA electrospun fiber mats. Accordingly, the antibacterial activities revealed that all the composite nanofiber mats exhibited excellent resistance against S. aureus and E. coli bacterial strains. In addition, in the cell toxicity study, all produced hybrids of nonwoven fiber mats induced a reduction in cell viability for the L929 fibroblast cells. Our results suggest that the designed and prepared nonwoven fiber mats may have good potential for use in the biomedical field, particularly in wound dressing applications.

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Preparation of surface-functionalized electrospun PVA nanowebs for potential remedy for SARS-CoV-2

Cited by 8 publications

References 32 publications

Superhydrophobic and highly moisture-resistant PVA@EC composite membrane for air purification

Superhydrophobic and highly moisture-resistant PVA@EC composite membrane for air purification

Application of Electrospun Water-Soluble Synthetic Polymers for Multifunctional Air Filters and Face Masks

Innovative Electrospun Nanofiber Mats Based on Polylactic Acid Composited with Silver Nanoparticles for Medical Applications

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