Preparation of Tea Tree Oil/Poly(styrene-butyl methacrylate) Microspheres with Sustained Release and Anti-Bacterial Properties

Lin, Guanquan; Chen, Huayao; Zhou, Hongjun; Zhou, Xinhua; Xu, Hengyong

doi:10.3390/ma11050710

Cited by 30 publications

(15 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was ascribed to the stretching vibration peak of the C-H bond. Absorption bands at 1126 cm −1 , related to the stretching vibration of the C-O bond of the tertiary alcohol in terpenes and terpineol, were observed [40]. This FTIR spectrum also shows a peak at 3450 cm −1 , ascribed to the O-H bond stretching vibration, and the 887 cm −1 , 864 cm −1 , and 799 cm −1 regions are ascribed to the Terpinen-4-ol compound [41].…”

Section: Ft-ir Analysismentioning

confidence: 82%

Reduced-Pressure Process for Fabricating Tea Tree Oil—Polyvinylpyrrolidone Electrospun Fibers

et al. 2022

View full text Add to dashboard Cite

Electrospun fibers containing tea tree oil (TTO) can be explored for practical applications due to the antimicrobial and anti-inflammatory activities of TTO. Considering that there are potentially toxic components in TTO, it is necessary to eliminate or reduce its content in the preparation process of TTO-doped electrospun fibers. In this work, electrospun TTO-PVP (polyvinylpyrrolidone) fibers containing an 18.18 wt.% decreased content of 1,8-Cineole were successfully fabricated by intense evaporation of a self-made reduced-pressure electrospinning (RP-ES) setup (as low as 94.4 kPa). In addition, such intense evaporation led to a morphology change, where a typical average fiber diameter increased from 0.831 to 1.148 μm, fewer and smaller beads in fibers, along with a rougher and grooves fiber surface. These morphology changes allowed Terpinen-4-ol to remain in the fiber for a more extended period. In addition, RP-ES proved the possibility for intense evaporation and continuous vapor removal by continuously environmental vacuum pumping of electrospinning.

show abstract

Section: Ft-ir Analysismentioning

confidence: 82%

Reduced-Pressure Process for Fabricating Tea Tree Oil—Polyvinylpyrrolidone Electrospun Fibers

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The peak at 1730 cm −1 and 1562 cm −1 ( Figure 9 b. C_A_ApII_w) represents ester bonds and carbonyl groups from the acid, respectively. It is clear from all this that the successful binding of chitosan to the structure of the cellulose material took place [ 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. Table 3 and Table 4 show the values of measurements made with a goniometer using droplet analysis and a tilting table (DSA30S).…”

Section: Resultsmentioning

confidence: 99%

Hydrothermal Synthesis of Chitosan and Tea Tree Oil on Plain and Satin Weave Cotton Fabrics

et al. 2022

View full text Add to dashboard Cite

The paper aimed at enhancing the antimicrobial activity of chitosan by using tea tree essential oil with the purpose of durably finishing cotton fabrics for use in a hospital environment. The influence of crosslinkers and catalysts on the possibility of obtaining stable bonds using hydrothermal in situ synthesis between cellulosic material and chitosan with and without tea tree essential oil was investigated in detail. The morphology of the sample surface before and after the treatment and textile care cycle was investigated using a field emission scanning electron microscopy (FE-SEM) and indicated the presence of chitosan and a thin film on all treated samples, which showed durability of the treatment. The FTIR spectra obtained by Fourier transform infrared spectroscopy (FTIR) using attenuated total reflection measurement technique (ATR) analysis, showed that all the samples tested recorded physicochemical changes in the structure. The analysis of the samples on the goniometer proved the hydrophilicity of the materials, with a film forming on the surface of the treated samples, which is extremely beneficial given the end use of dressing samples to promote wound healing. The presence of a significant amount of bound chitosan with tea tree oil was confirmed by measuring the mass per unit area of the samples after the treatment and textile care cycles. The results of antimicrobial efficacy show that the materials treated with chitosan were resistant to bacteria and fungi in most cases, but only the samples treated in Bath I showed a zone of inhibition against the fungus Candida albicans, indicating the positive effect of tea tree essential oil.

show abstract

“…[46] In this assay, the stability of TTO and TTO-ME at variable concentrations (100-1000 µl/ml) was tested and compared it with its terpenoid content. [47]…”

Section: Stability Testing Of Tto-mementioning

confidence: 99%

Untitled

Singh

2019

AJP

View full text Add to dashboard Cite

Aim: The aim of the study was to develop oil-in-water microemulsion (ME) system for Melaleuca alternifolia for targeting skin disorders. Materials and Methods: The formulation of ME system was done through the water titration method, which involved various oils, water, surfactants, and cosurfactants. The existence zones of ME were determined by constructing ternary phase diagrams, where surfactants and cosurfactants (S mix) were taken in different ratios along with different combinations of oil and S mix. Quantitative estimation of tea tree oil (TTO) was performed using gas chromatography-mass spectrometry followed by total terpenoid estimation, and thereafter, solubility studies of TTO were performed using various excipients. TTO-ME was fabricated and characterized using modern characterization techniques (DLS, transmission electron microscopy, and Fourier transform infrared) along with statistical validation and in vitro drug release assessment. Results and Discussion: The optimized TTO loaded MEs (TTO ME) showed the particle size range between 32 and 160 nm with poly dispersibility index of 0.297 and zeta potential of −3.19 mv with almost spherical morphology. The optimized formulation showed the sustained release of the therapeutic compound and was found to be stable at room temperature for 1 year, suggesting being a promising formulation against dermal infections. Conclusion: TTO was successfully loaded in thermodynamically stable ME system which enhanced its permeation through the transdermal route. Therefore, a novel drug delivery system was introduced, which can be studied on various in vitro and in vivo models further to establish its better therapeutic efficacy for various skin disorders.

show abstract

Preparation of Tea Tree Oil/Poly(styrene-butyl methacrylate) Microspheres with Sustained Release and Anti-Bacterial Properties

Cited by 30 publications

References 39 publications

Reduced-Pressure Process for Fabricating Tea Tree Oil—Polyvinylpyrrolidone Electrospun Fibers

Reduced-Pressure Process for Fabricating Tea Tree Oil—Polyvinylpyrrolidone Electrospun Fibers

Hydrothermal Synthesis of Chitosan and Tea Tree Oil on Plain and Satin Weave Cotton Fabrics

Untitled

Contact Info

Product

Resources

About