Preparation of temperature-responsive nanomicelles with AIE property as fluorescence probe for detection of Fe3+ and Fe2+

Hou, Xinhui; Song, Yifan; Lv, Yupeng; Wang, Peiyao; Chen, Kun; Li, Guiying; Guo, Lei

doi:10.1016/j.saa.2022.122254

Cited by 10 publications

(1 citation statement)

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“…Iron is a transition metal, which is the most abundant in human body. [1][2][3][4][5] It plays an important role in cellular events and in various biological processes such as DNA synthesis, enzymatic reaction, oxygen transition and so on [6]. Its content can be as high as 3-4 g in an adult and much higher than other transition metals.…”

Section: Introductionmentioning

confidence: 99%

Rhodamine-based Fluorescent Probe With Quick Response and High Selectivity for Imaging Labile Ferrous Iron in Living Cells and Zebrafish

Wang,

Chen,

Liu

et al. 2023

J Fluoresc

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The transition between its various oxidation states of Iron plays a crucial part in various chemical transformation of cells. Misregulation of iron can give rise to the iron-catalyzed reactive oxygen species disorder which have been linked to a variety of diseases, so it is crucial to monitor the labile iron pool in vivo for clinical diagnosis. According to iron autoxidation and hydrogen abstraction reaction, we reported a novel "off-on" uorescent probe to response to ferrous (Fe 2+ ) both in solutions and biological systems.The probe responds to Fe 2+ with good selectivity toward competing metal ions. What's more, the probe presents signi cant uorescent enhancement to Fe 2+ in less than 1 min, making real-time sensing in biological system possible. The applications of the probe in bioimaging revealed the changes in labile iron pool by iron autoxidation or diverse stimuli.

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Section: Introductionmentioning

confidence: 99%