Preparation of three regioisomeric ionic liquid stationary phases and investigation of their retention behavior

A C4-modified bipyridinium multi-mode stationary phase for reversed phase, hydrophilic interaction and ion exchange chromatography

“…[31][32][33] ILs showed two applications in HPLC, one is as a mobile phase additive, and the other is as a stationary phase by bonding. 21,22,[34][35][36][37][38] ILs can induce hydrophobic, hydrophilic, pp interaction, electrostatic interaction, hydrogen bond interaction, and ionic dipole interaction. Therefore, ionic liquids might be used in the design of mixed-mode chromatographic stationary phases and promote the development of mixed-mode chromatographic stationary phases.…”